Publikationen 2011


Kiss EA, Vonarbourg C, Kopfmann S, Hobeika E, Finke D, Esser C, Diefenbach A: Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles. Science 334 (6062): 1561-1565, 2011. [pubmed]

Guarda G, Braun M, Staehli F, Tardivel A, Mattmann C, Förster I, Farlik M, Decker T, Du Pasquier RA, Romero P, Tschopp J: Type I interferon inhibits interleukin-1 production and inflammasome activation. Immunity 34(2): 213-223, 2011. [pubmed]

Weber C, Meiler S, Döring Y, Koch M, Drechsler M, Megens RT, Rowinska Z, Bidzhekov K, Fecher C, Ribechini E, van Zandvoort MA, Binder CJ, Jelinek I, Hristov M, Boon L, Jung S, Korn T, Lutz MB, Förster I, Zenke M, Hieronymus T, Junt T, Zernecke A: CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice. J Clin Invest 121(7): 2898–2910, 2011. [pubmed]

Rey G, Cesbron F, Rougemont J, Reinke H, Brunner M, Naef F: Genome-wide and phase-specific DNA-binding rhythms of BMAL1 control circadian output functions in mouse liver. PLoS Biology 9(2): e1000595, 2011. [pubmed]

Filipiak-Pittroff B, Schnopp C, Berdel D, Naumann A, Sedlmeier S, Onken A, Rodriguez E, Fölster-Holst R, Baurecht H, Ollert M, Ring J, Cramer C, von Berg A, Bauer CP, Herbarth O, Lehmann I, Schaaf B, Koletzko S, Wichmann HE, Heinrich J, Weidinger S, on behalf of the GINIplus and LISAplus study groups. Predictive value of food sensitization 1 and filaggrin mutations in children with eczema. J Allergy Clin Immunol 128(6): 1235-1241, 2011. [pubmed]

Koletzko S, Filipiak-Pittroff B, von Berg A, Grübl A, Heinrich J, Krämer U, Wichmann HE, Bauer CP, Reinhardt D, Berdel D: Supplementation with cow's milk at birth is not recommended. J Allergy Clin Immunology 127(3): 836-838, 2011.

Scharf A, Grozdanov PN, Veith R, Kubitscheck U, Meier UT, von Mikecz A: Distant positioning of proteasomal proteolysis relative to actively transcribed genes. Nucleic Acids Research 39(11): 4612-4627, 2011. [pubmed]

Zschauer TC, Kunze K, Jakob S, Haendeler J, Altschmied J: Oxidative stress-induced degradation of Thioredoxin-1 and apoptosis is Iinhibited by Thioredoxin-1-actin interaction in endothelial cells. Arterioscler Thromb Vasc Biol 31(3): 650-656, 2011. [pubmed]

Tegenge MA, Rockel TD, Fritsche E*, Bicker G*: Nitric oxide stimulates human neural progenitor cell migration via cGMP-mediated signal transduction. Cell Mol Life Sci 68(12): 2089-2099, 2011. (* corresponding authors) [pubmed]

Rzehak P, Sausenthaler S, Koletzko B, Reinhardt D, von Berg A, Krämer U, Berdel D, Bollrath C, Grübl A, Bauer C P, Wichmann H-E, Heinrich J, for the GINI-plus study group. Long-term effects of hydrolyzed protein infant formulas on growth-extended follow-up to 10 years of age: results from the German Infant Nutrional Intervention Study (GINI). Am J Clin Nutr 94(6): 1803S-1807S, 2011. [pubmed]

Cramer C, Link E, Bauer CP, Hoffmann U, von Berg A, Lehmann I, Herbarth O, Borte M, Schaaf B, Sausenthaler S, Wichmann H-E, Heinrich J, Krämer U: Association between attendance of day care centres and increased prevalence of eczema in the German birth cohort sutdy LISAplus. Allergy 66(1): 68-75, 2011. [pubmed]

Hastan D, Fokkens WJ, Bachert C, Newson RB, Bislimovska J, Bockelbrink A, Bousquet PJ, Brozek G, Bruno A, Dahlén SE, Forsberg B, Gunnbjörnsdóttir M, Kasper L, Krämer U, Kowalski ML, Lange B, Lundbäck B, Salagean E, Todo-Bom A, Tomassen P, Toskala E, van Drunen CM, Bousquet J, Zuberbier T, Jarvis D, Burney P: Chronic rhinosinusitis in Europe - an underestimated disease. A GA(2) LEN study. Allergy 66(9): 1216-1223, 2011. [pubmed]

Schmitt J, Chen CM, Apfelbacher C, Romanos M, Lehmann I, Herbarth O, Schaaf B, Krämer U, von Berg A, Wichmann HE, Heinrich J, the LISA-plus Study Group: Infant eczema, infant sleeping problems and mental health at 10 years of age: The prospective birth-cohort study LISAplus. Allergy 66(3): 404-411, 2011. [pubmed]

Tischer CG, Hohmann C, Thiering E, Herbarth O, Muller A, Henderson J, Granell R, Fantini MP, Luciano L, Bergstrom A, Kull I, Link E, von BA, Kuehni CE, Strippoli MP, Gehring U, Wijga A, Eller E, Bindslev-Jensen C, Keil T, Heinrich J. Meta-analysis of mould and dampness exposure on asthma and allergy in eight European birth cohorts: an ENRIECO initiative. Allergy 66(12): 1570-1579, 2011. [pubmed]

Tomassen P, Newson RB, Hoffmans R, Lötvall J, Cardell LO, Gunnbjörnsdóttir M, Thilsing T, Matricardi P, Krämer U, Makowska JS, Brozek G, Gjomarkaj M, Howarth P, Loureiro C, Toskala E, Fokkens W, Bachert C, Burney P, Jarvis D:
Reliability of EP3OS symptom criteria and nasal endoscopy in the assessment of chronic rhinosinusitis - a GA(2)LEN study. Allergy 66 (4): 556-561, 2011. [pubmed]

Jux B, Kadow S, Luecke S, Rannug A, Krutmann J, Esser C: The Aryl Hydrocarbon Receptor Mediates UVB Radiation-Induced Skin Tanning. J Invest Dermatol 131(1): 203-210, 2011. [pubmed]

Fuks K, Viehmann A, Moebus S, Nonnemacher M, Möhlenkamp S, Dragano N, Jakobs H, Erbel R, Jöckel KH, Hoffmann B on behalf of the Heinz Nixdorf Recall Investigative Group: Long-term urban particulate air pollution, traffic noise and arterial blood pressure.  Environ Health Perspect 119(12): 1706-1711, 2011. [pubmed]

Peinemann F, Moebus S, Dragano N, Möhlenkamp S, Lehmann N, Zeeb H, Erbel R, Jöckel KH, Hoffmann B: Second-hand smoke exposure and coronary artery calcification among non-smoking participants of a population-based cohort. Environ Health Perspect 119(11): 1556-1561, 2011. [pubmed]

Tischer C, Gehring U, Chen CM, Kerkhof M, Koppelman G, Sausenthaler S, Herbarth O, Schaaf B, Lehmann I, Krämer U, Berdel D, von Berg A, Bauer CP, Koletzko S, Wichmann HE, Brunekreef B, Heinrich J: Respiratory health in children and indoor exposure to (1,3)-{beta}-D-glucan, EPS mould components, and endotoxin. Eur Respir J 37(5): 1050-1059, 2011. [pubmed]

Kadow S, Jux B, Zahner SP, Wingerath B, Chmill S, Clausen BE, Hengstler J, Esser C: Aryl hydrocarbon receptor is critical for homeostasis of invariant gamma-delta T cells in the murine epidermis. J Immunology 187(6): 3104-3110, 2011. [pubmed]

Vordenbäumen S, Braukmann A, Petermann K, Scharf A, Bleck E, von Mikecz A, Jose J, Schneider M: Casein alpha s1 is expressed by human monocytes and upregulates the production of GM-CSF via p38 MAPK. J Immunol 186(1): 592-601, 2011. [pubmed]

Specht S, Frank JK, Alferink J, Dubben B, Layland LE, Denece G, Bain O, Förster I, Kirschning CJ, Martin C, Hoerauf A: CCL17 controls mast cells for the defense against filarial larval entry. J Immunol 186: 4845-4852, 2011. [pubmed]

Röck K, Grandoch M, Majora M, Krutmann J, Fischer JW: Collagen fragments inhibit hyaluronan synthesis in skin fibroblasts in response to UVB: New insights into mechanisms of matrix remodelling. J Biol Chem 286 (20): 18268-18276, 2011. [pubmed]

Scherbart AM, Langer J, Bushmelev A, van Berlo D, Haberzettl P, van Schooten FJ, Schmidt AM, Rose CR, Schins RPF, Albrecht C: Uptake, inflammatory and oxidative stress responses of titanium dioxide in alveolar macrophages: A question of size? Part Fibre Toxicol 8(1): 31, 2011. [pubmed]

Speckmann B, Bidmon HJ, Pinto A, Anlauf M, Sies H, Steinbrenner H: Induction of glutathione peroxidase 4 expression during enterocytic cell differentiation. J Biol Chem 286(12): 10764-10772, 2011. [pubmed]

Arnhold F, von Mikecz A: Quantitative feature extraction reveals the status quo of protein fibrillation in the cell nucleus. Integrative Biology 3(7): 761-769, 2011. [pubmed]

Krefis AC, Schwarz NG, Nkrumah B, Acquah S, Loag W, Oldeland J, Sarpong N, Adu-Sarkodie Y, Ranft U, May J:
Spatial analysis of land cover determinants of malaria incidence in the ashanti region, ghana. PLoS One 6(3): e17905, 2011. [pubmed]

Tse BW, Russell PJ, Lochner M, Förster I, Power CA: IL-18 inhibits growth of murine orthotopic prostate carcinomas via both adaptive and innate immune mechanisms. PLoS One 6 (9): e24241, 2011. [pubmed]

Bayer M, Proksch P, Felsner I, Brenden H, Kohne Z, Walli R, Duong TN, Götz C, Krutmann J, Grether-Beck S:
Photoprotection against UVAR: Effective triterpenoids require a lipid raft stabilizing chemical structure.
Exp Dermatol 20 (11): 955-958, 2011. [pubmed]

Farwick M, Grether-Beck S, Marini A, Maczkiewitz U, Lange J, Köhler T, Lersch P, Falla T, Felsner I, Brenden H, Jaenicke T, Franke S, Krutmann J: Bioactive tetrapeptide GEKG boosts extracellular matrix formation: in vitro and in vivo molecular and clinical proof. Exp Dermatol 20 (7): 602-604, 2011. [pubmed]

Marionnet C, Grether-Beck S, Seité S, Marini A, Jaenicke T, Lejeune F, Bastien P, Rougier A, Bernerd F, Krutmann J: A broad-spectrum sunscreen prevents UVA radiation-induced gene expression in reconstructed skin in vitro and in human skin in vivo. Exp Dermatol 20(6): 477-482, 2011. [pubmed]

Ghiazza M, Scherbart AM, Fenoglio I, Grendene F, Turci F, Martra G, Albrecht C, Schins RP, Fubini B: Surface iron inhibits quartz-induced cytotoxic and inflammatory responses in alveolar macrophages. Chem Res Toxicol 24(1): 99-110, 2011. [pubmed]

Werner C, Gensch C, Pöss J, Haendeler J, Böhm M, Laufs U: Pioglitazone activates aortic telomerase and prevents stress-induced endothelial apoptosis. Atherosclerosis 216(1): 23-34, 2011. [pubmed]

Gerloff K, Albrecht C, Boots AW, Förster I, Schins RPF. Particles which may occur in food or food packaging can exert cytotoxicity and (oxidative) DNA damage in target cells of the human intestine. Letter to the editor. Nanotoxicology 5: 282-283, 2011.

Wessels A, van Berlo D, Boots AW, Gerloff K, Scherbart AM, Cassee F, Gerlofs-Nijland M, Van Schooten F, Albrecht C, Schins RPF: Oxidative stress and DNA damage responses in rat and mouse lung to inhaled carbon nanoparticles. Nanotoxicology 5: 66-78, 2011. [pubmed]

Winter M, Beer HD, Hornung V, Krämer U, Schins RPF, Förster I: Activation of the inflammasome by amorphous silica and TiO2 nanoparticles in murine dendritic cells.  Nanotoxicology 5: 326-340, 2011. [pubmed]

Perner D, Vierkötter A, Sugiri D, Matsui M, Ranft U, Esser C, Ethève S, Goralczyk R, Kaneko N, Yamamoto A, Morita A, Krutmann J, Krämer U: Association between sun-exposure, smoking behaviour and plasma antioxidant levels with the different manifestation of skin ageing signs between Japanese and German women – A pilot study. J Dermatol Sci 62(2): 138-140, 2011.

Sodenkamp JC, Behrends J, Förster I, Müller W, Ehlers S, Hölscher C: gp130 on macrophages/granulocytes modulates inflammation during experimental tuberculosis. Eur J Cell Biol 90(6-7): 505-514, 2011. [pubmed]

Bothe H*, Gassmann K*, Götz C, Fritsche E, Abel J, Haarmann-Stemmann T: Epigallocatechin-3-gallate does not affect the activity of enzymes involved in metabolic activation and cellular excretion of benzo[a]pyrene in human colon carcinoma cells. Toxicology Letters 203(3): 258-264, 2011. (*equal contribution) [pubmed]

Kasper-Sonnenberg M, Sugiri D, Wurzler S, Ranft U, Dickel H, Wittsiepe J, Hölzer J, Lemm F, Eberwein G, Altmeyer P, Kraft M, Krämer U, Wilhelm M: Prevalence of nickel sensitization and urinary nickel content of children are increased by nickel in ambient air. Environ Res 111(2): 266-273, 2011. [pubmed]

Tiesler CM, Chen CM, Sausenthaler S, Herbarth O, Lehmann I, Schaaf B, Krämer U, von Berg A, von Kries R, Wichmann HE, Heinrich J; The LISA Study Group: Passive smoking and behavioural problems in children: Results from the LISAplus prospective birth cohort study. Environ Res 111(8): 1173-1179, 2011. [pubmed]

Rzehak P, Koletzko S, Koletzko B, Sausenthaler S, Reinhardt D, Grübl A, Bauer CP, Krämer U, Bollrath C, von Berg A, Berdel D, Wichmann HE, Heinrich J, for the GINI Study Group: Growth of infants fed formula rich in canola oil (low erucic acid rapeseed oil). Clin Nutr 30(3): 339-345, 2011. [pubmed]

Brossette T, Hundsdörfer C, Kröncke KD, Sies H, Stahl W: Direct evidence that (-)-epicatechin increases intric oxide levels in human endothelial cells. Eur J Nutr 50: 595-599, 2011. [pubmed]

Pinto A, Speckmann B, Sies H, Steinbrenner H: Delaying insulin signal transduction in skeletal muscle cells. J Inorganic Biochem 105: 812-820, 2011. [pubmed]

Franck U, Herbarth O, Röder S, Schlink U, Borte M, Diez U, Krämer U, Lehmann I: Respiratory effects of indoor particles in young children are size dependent. Sci Total Environ 409(9):1621-1631, 2011. [pubmed]

Eckers A, Sauerbier E, Anwar-Mohamed A, Hamann I, Esser C, Schroeder P, El-Kadi AO, Klotz LO: Detection of a functional xenobiotic response element in a widely employed FoxO-responsive reporter construct. Arch Biochem Biophys 516(2): 138-145, 2011. [pubmed]

Apfelbacher CJ, Krämer U: Erratum re: prevalence of overweight and obesity in East and West German children in the decade after reunification: population-based series of cross-sectional studies. J Epidemiol Community Health 65(1): 86, 2011.

Thiering E, Brüske I, Kratzsch J, Thiery J, Sausenthaler S, Meisinger C, Koletzko S, Bauer CP, Schaaf B, von Berg A, Berdel D, Lehmann I, Herbarth O, Krämer U, Wichmann HE, Heinrich J; for the GINIplus and LISAplus Study Groups: Prenatal and postnatal tobacco smoke exposure and development of insulin resistance in 10 year old children. Int J Hyg Environ Health 214(5): 361-368, 2011. [pubmed]

Lukosz M, Mlynek A, Czypiorski P, Altschmied J, Haendeler J: The transcription factor Grainyhead like 3 (GRHL3) affects endothelial cell apoptosis and migration in a NO-dependent manner. Biochem Biophys Res Commun 412(4): 648-553, 2011. [pubmed]

Sørensen M, Hvidberg M, Hoffmann B, Andersen ZJ, Nordsborg RB, Lillelund KG, Jakobsen J, Tjønneland A, Overvad K, Raaschou-Nielsen O: Exposure to road traffic and railway noise and associations with blood pressure and self-reported hypertension: a cohort study. Environmental Health 10(1): 92, 2011. [pubmed]

Krefis AC, Schwarz NG, Krüger A, Fobil J, Nkrumah B, Acquah S, Loag W, Sarpong N, Adu-Sarkodie Y, Ranft U, May J:
Modeling the Relationship between Precipitation and Malaria Incidence in Children from a Holoendemic Area in Ghana. Am J Trop Med Hyg 84(2): 285-291, 2011. [pubmed]

Standl M, Sausenthaler S, Lattka E, Koletzko S, Bauer CP, Wichmann HE, von Berg A, Berdel D, Krämer U, Schaaf B, Röder S, Herbarth O, Klopp N, Koletzko B, Heinrich J; for the GINIplus and LISAplus Study Group: FADS gene variants modulate the effect of dietary fatty acid intake on allergic diseases in children. Clin Exp Allergy 41(12): 1757-1766, 2011. [pubmed]

Breitfelder A, Wenig CM, Wolfenstetter SB, Rzehak P, Menn P, John J, Leidl R, Bauer CP, Koletzko S, Röder S, Herbarth O, von Berg A, Berdel D, Krämer U, Schaaf B, Wichmann HE, Heinrich J; the GINI-plus, LISA-plus Study Groups: Relative weight-related costs of healthcare use by children-Results from the two German birth cohorts, GINI-plus and LISA-plus. Econ Hum Biol 9(3): 302-315, 2011. [pubmed]

Leyendecker M, Korsten P, Reinehr R, Speckmann B, Schmoll D, Scherbaum WA, Bornstein SR, Barthel A, Klotz LO:
Ceruloplasmin expression in rat liver cells is attenuated by insulin: Role of FoxO transcription factors. Horm Metab Res 43 (4): 268-274, 2011. [pubmed]

Sausenthaler S, Stadl M, Buyken A, Rzehak P, Koletzko S, Bauer CP, Schaaf B, von Berg A, Berdel D, Borte M, Herbart O, Lehmann I, Krämer U, Wichmann H-E, Heinrich J: Regional and socioeconomic differences in food, nutrient and supplement intake in school-age children in Germany. Results from the GINIplus and the LISAplus Study. Public Health Nutrition 14 (10): 1724-1735, 2011. [pubmed]

Germing A, Gotzmann M, Schikowski T, Vierkötter A, Ranft U, Kramer U, Mugge A: High frequency of diastolic dysfunction in a population-based cohort of elderly women - but poor association with the symptom dyspnea. BMC Geriatrics 11(1): 71, 2011. [pubmed]

Steinbrenner H, Speckmann B, Pinto A, Sies H: High selenium intake and increased diabetes risk: experimental evidence for interplay between selenium and carbohydrate metabolism. J Clin Biochem Nutr 48 (1): 40-45, 2011. [pubmed]

Germing A, Gotzmann M, Schikowski T, Vierkötter A, Ranft U, Mügge A: Diastolic dysfunction without abnormalities in left atrial and left ventricular geometry does not affect quality of life in elderly women. Exp Clin Cardiol 16 (2): 37-39, 2011. [pubmed]

Übersichtsarbeiten, Buchbeiträge u.a.


Elsner P, Fluhr JW, Gehring W, Kerscher MJ, Krutmann J, Lademann J, Makrantonaki E, Wilhelm KP, Zouboulis CC: Anti-aging data and support claims – consensus statement. J Dtsch Dermatol Ges 9, Suppl 3: S1-S32, 2011.

Fritsche E, Gassmann K, Schreiber T: Neurospheres as a model for developmental neurotoxicity testing. In: In Vitro Neurotoxicology: Methods and Protocols, Methods in Molecular Biology, vol. 758. Lucio G. Costa et al. (eds.), Springer Science+Business Media, LLC 2011, pp. 99-114.

Haarmann-Stemmann T, Abel J: Influence of HIF-1a and Nrf2 on AHR mediated gene expression, toxicity and biological functions. In: The AH Receptor in Biology and Toxicology. Raimo Pohjanvirta (ed). Wiley-VCH, Weinheim 2011, ISBN 978-0-470-60182-2.

Humbert P, Binda D, Robin S, Krutmann J: Beauty from inside: Nutrition-based strategies in cosmetic dermatology. In: Nutrition für healthy skin: Strategies for clinical and cosmetic practice. Krutmann J, Humbert P (eds.). Springer 2011, pp. 189-196.

Krutmann J: Hautalterung / Anti-Aging-Strategien (editorial). Hautarzt 62(8): 576, 2011.

 Krutmann J: Wie die Sonne unsere Haut altern lässt. Die Dermis als treibende Kraft.  Hautarzt 62(8): 588-590, 2011.

Krutmann J. Skin aging. In: Nutrition für healthy skin: Strategies for clinical and cosmetic practice. Krutmann J, Humbert P (eds.). Springer 2011, pp.15-24.

Krutmann J, Luger T: Empfindliche Haut. Hautarzt 62 (12) 892, 2011.

Krutmann J, Humbert P (Eds.): Nutrition für healthy skin: Strategies for clinical and cosmetic practice. Springer 2011, 208 pp.

Mang R, Stege H, Krutmann J: Mechanisms in phototoxic and photoallergic reactions. In: Contact Dermatitis, 5th ed, (Menné T, Frosch P, eds), Springer Berlin, Heidelberg 2011, pp. 155-163.

Marini, A: Schönheit in innen – Funktioniert das wirklich? Hautarzt 62(8): 614-617, 2011.

Monastier C, Mac-Mary S, Krutmann J: How to prove safety and efficacy in nutrition based intervention studies for human skin. In: Nutrition für healthy skin: Strategies for clinical and cosmetic practice. Krutmann J, Humbert P (eds.). Springer 2011, pp. 181-188.

Riedel N, Hoffman B, Fuks K, Jöckel KH, Dragano N: Gesundheitliche Ungleichheit in der Stadt: Eine gemeinsame Bewertung von sozialen und umweltbezogenen Belastungen im Ruhrgebiet - Health inequalities in the city: assessing the concurrence of social and environmental risks in the Ruhr Area. Umwelt und Mensch – Informationsdienst 2: 89-94, 2011.

Verner MA, Bouchard M, Fritsche E, Charbonneau M, Haddad S: In vitro neurotoxicity data in human risk assessment of polybrominated diphenyl ethers (PBDEs): Overview and perspectives. Toxicol In Vitro 25 (8): 1509-1515, 2011. [pubmed]

 Vierkötter A: Umweltverschmutzung und Hautalterung.  Hautarzt 62(8): 577-581, 2011.

Loft S, Schins RPF, Møller P: Particulates and oxidative stress. In: Cardiovascular Effects of Inhaled Ultrafine and Nano-Sized Particles. Cassee FR, Mills NL, Newby DE (Eds). John Wiley and Sons, New Jersey, USA , pp. 251-271, 2011.

Schroeder P, Krutmann J: Infrared A radiation effects on the skin. Piel 26 (6): 259-262, 2011.

Stutte S, Gerbitzki N, Novak N, Förster I: Expression and function of CCL17 in atopic dermatitis. In: Atopic Dermatitis. Ed. J. Esparza-Gordillo, InTech2011, ISBN 978-953-308-67-5