Originalarbeiten

Werner CM, Fürster T, Widmann T, Pöss J, Roggia C, Hanhoun M, Scharhag J, Büchner N, Meyer T, Kindermann W, Haendeler J, Böhm M, Laufs U: Physical exercise prevents cellular senescence in circulating leukocytes and in the vessel wall. Circulation 120: 2438-2447, 2009.
 

Ale-Agha N, Galban S, Sobieroy C, Abdelmohsen K, Gorospe M, Sies H, Klotz LO: HuR regulates gap junctional intercellular communication by controlling β-catenin levels and adherens junction integrity. Hepatology 50 (5): 1567-1576, 2009.
 

Sydlik U, Gallitz I, Albrecht C, Abel J, Krutmann J, Unfried K: The compatible solute ectoine protects against nanoparticle-induced neutrophilic lung inflammation. Am J Respir Crit Care Med 180 (1): 29-35, 2009.
 

Gros E, Bussmann C, Bieber T, Förster I, Novak N: Expression of chemokines and chemokine receptors in lesional and non-lesional skin of atopic dermatitis. J Allergy Clin Immunol 124 (4): 753-760, 2009.
 

Moors M, Rockel TD, Abel J, Cline JE, Gassmann K, Schreiber T, Schuwald J, Weinmann N, Fritsche E: Human neurospheres as three-dimensional cellular systems for developmental neurotoxicity testing. Environ Health Perspect 117 (7): 1131-1138. 2009.
 

Dalla Rosa I, Goffart S, Wurm M, Wiek C, Essmann F, Sobek S, Schroeder P, Zhang H, Krutmann J, Hanenberg H, Schulze-Osthoff K, Mielke C, Pommier Y, Boege F, Christensen MO: Adaptation of topoisomerase I paralogs to nuclear and mitochondrial DNA. Nucleic Acids Res 37 (19): 6414-6428, 2009.
 

Haendeler J, Dröse S, Büchner N, Jakob S, Altschmied J, Goy C, Spyridopoulos I, Zeiher AM, Brandt U, Dimmeler S: Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage. Arterioscler Thromb Vasc Biol 29 (6): 929-935, 2009.
 

Rzehak P, Sausenthaler S, Koletzko S, Reinhardt D, von Berg A, Krämer U, Berdel D, Bollrath C, Grübl A, Bauer CP, Wichmann HE, Heinrich J; German Infant Nutritional Intervention Study Group: Short- and long-term effects of feeding hydrolyzed protein infant formulas on growth at < or = 6 y of age: results from the German Infant Nutritional Intervention Study. Am J Clin Nutr 89 (6): 1846-1856, 2009.
 

Schwarz C, Ranft U, Piechotowski I, Childs JE, Brockmann SO: Risk Factors for human infection with Puumala virus, Southwestern Germany. Emerging Infectious Diseases 15 (7): 1032-1039, 2009.
 

Chen CM, Weidinger S, Klopp N, Sausenthaler S, Bischof W, Herbarth O, Bauer M, Borte M, Schaaf B, Lehmann I, Behrendt H, Krämer U, Berdel D, von Berg A, Bauer CP, Koletzko S, Illig T, Wichmann HE, Heinrich J; the LISA and GINI Study Group: Common variants in FCER1A influence total serum IgE levels from cord blood up to six years of life. Allergy 64 (9): 1327-1332, 2009.
 

Jux B, Kadow S, Esser C: Langerhans cell maturation and contact hypersensitivity are impaired in aryl hydrocarbon receptor-null mice. J Immunol 182 (11): 6709-6717, 2009.
 

Majora M, Wittkampf T, Schürmann B, Bernerd F, Schroeder P, Krutmann J: Functional consequences of mitochondrial DNA deletions in human skin fibroblasts: Increased contractile strength in collagen lattices is due to oxidative stress-induced lysyl oxidase activity. Am J Pathol 175 (3): 1019-1029, 2009.
 

Catalgol B, Ziaja I, Breusing N, Jung T, Hoehn A, Alpertunga B, Schroeder P, Chondrogianni N, Gonos ES, Petropoulos I, Friguet B, Klotz LO, Krutmann J, Grune T: The proteasome is an integral part of solar ultraviolet a radiation-induced gene expression. J Biol Chem 284 (44): 30076-30086, 2009.
 

Gerlofs-Nijland ME, Rummelhard M, Boere JF, Leseman DLAC, Duffin R, Schins RPF, Borm PJA, Sillanpää M, Salonen RO, Cassee FR: Particle induced toxicity in relation to Transition Metal and Polycyclic Aromatic Hydrocarbon contents. Environ Sci Technol 43 (13): 4729-4736, 2009.
 

Gerloff K, Albrecht C, Boots AW, Förster I, Schins RPF: Cytotoxicity and oxidative DNA damage by nanoparticles in human intestinal Caco-2 cells. Nanotoxicology 3 (4): 355-364,  2009.
 

Van Berlo D, Haberzettl P, Gerloff K, Li H, Scherbart AM, Albrecht C, Schins RPF: Investigation of the cytotoxic and proinflammatory effects of cement dusts in rat alveolar macropages. Chemical Research in Toxicology 22 (9): 1548-1558, 2009.
 

Tessema TS, Schwamb B, Lochner M, Förster I, Jakobi V, Petry F: Dynamics of gut mucosal and systemic Th1/Th2 cytokine responses in interferon-gamma and interleukin-12p40 knock out mice during primary and challenge Cryptosporidium parvum infection. Immunobiology 214 (6): 454-466, 2009.
 

Reim D, Westenfelder K, Kaiser-Moore S, Schlautkötter S, Holzmann B, Weighardt H: Role of T cells for cytokine production and outcome in a model of acute septic peritonitis. Shock 31 (3): 245-250, 2009.
 

Esser C, Jux B, Kadow S, Chmill S, Hübinger J, Frericks M: Cell specific action and toxicity of the AhR: Focus immune system. Toxicol Lett 189, Suppl. 1, S55, 2009.
 

Ranft U, Schikowski T, Sugiri D, Krutmann J, Krämer U: Long-term exposure to traffic-related particulate matter impairs cognitive function in the elderly. Environ Res 109 (8): 1004-1011, 2009.
 

Krämer U, Sugiri D, Ranft U, Krutmann J, von Berg A, Berdel D, Behrendt H, Kuhlbusch T, Hochadel M, Wichmann H-E, Heinrich J: Eczema, respiratory health and traffic related air pollution in birth cohorts from small-town areas. 
J Dermatol Sci 56 (2): 99-105, 2009.
 

Vierkötter A, Ranft U, Krämer U, Sugiri D, Reimann V, Krutmann J: The SCINEXA: A novel, validated score to simultaneously assess and differentiate between intrinsic and extrinsic skin ageing. 
 J Dermatol Sci 53 (3): 207-11, 2009.

Nawrot T, Kuenzli N, Sunyer J, Shi T, Moreno T, Viana M, Heinrich J, Forsberg B, Kelly F, Muhamed SM, Nemery B, Borm P: Oxidative Properties Of Ambient Pm2.5 And Elemental Composition: Heterogeneous Associations In 19 European Cities. Atmospheric Environment 43: 4595-4602, 2009.
 

Baulig A, Singh S, Marchand A, Schins R, Barouki R, Garlatti M, Marano F, Baeza-Squiban A: Role of Paris PM(2.5) components in the pro-inflammatory response induced in airway epithelial cells. Toxicology 261 (3): 126-135, 2009.
 

Eckers A, Reimann K, Klotz LO: Nickel and copper ion-induced stress signaling in human hepatoma cells: Analysis of phosphoinositide 3‘-kinase/Akt signaling. Biometals 22 (2): 307-316, 2009.
 

Herberth G, Gubelt R, Röder S, Krämer U, Schins RP, Diez U, Borte M, Heinrich J, Wichmann HE, Herbarth O, Lehmann I: Increase of inflammatory markers after indoor renovation activities: The LISA birth cohort study. Pediatr Allergy Immunol 20 (6): 563-570, 2009.
 

Mues C, Zhou J, Manolopoulos KN, Korsten P, Schmoll D, Klotz LO, Bornstein SR, Klein HH, Barthel A: Regulation of glucose-6-phosphatase gene expression by insulin and metformin. Horm Metab Res 41 (10): 730-735, 2009.
 

Ale-Agha N, Albrecht C, Klotz LO: 
Loss of gap junctional intercellular communication in rat lung epithelial cells exposed to quartz particles.
Biochem Biophys Res Commun 390 (1): 44-47, 2009.

Speckmann B, Sies H, Steinbrenner H: Attenuation of hepatic expression and secretion of selenoproteins. Biochem Biophys Res Commun 387: 158-163, 2009.
 

Rzehak P, Sausenthaler S, Koletzko S, Bauer CP, Schaaf B, von Berg A, Berdel D, Borte M, Herbarth O, Krämer U, Fenske N, Wichmann HE, Heinrich J: Period-specific growth, overweight and modification by breastfeeding in the GINI and LISA birth cohorts up to age 6 years. Eur J Epidemiol 24 (8): 449-467, 2009.
 

Albrecht C, Scherbart AM, Berlo D, Braunbarth CM, Schins RPF, Scheel J: Evaluation of cytotoxic effects and oxidative stress with hydroxyapatite dispersions of different physicochemical properties in rat NR8383 cells and primary macrophages. Toxicology in Vitro 23 (3): 520-530, 2009.
 

Chen M, von Mikecz A: Nanoparticle-induced cell culture models for neurodegenerative protein aggregation diseases. Inhalation Toxicology 21 (S1): 110-114, 2009.
 

Jalava PI, Hirvonen MR, Sillanpää M, Pennanen AS, Happo MS, Hillamo R, Cassee FR, Gerlofs-Nijland M, Borm PJ, Schins RP, Janssen NA, Salonen RO: Associations of urban air particulate composition with inflammatory and cytotoxic responses in RAW 246.7 cell line. Inhalation Toxicology 21 (12): 994-1006, 2009.
 

Hoffmann B, Kolahgar B, Rauchfuss K, Eberwein G, Franzen-Reuter I, Kraft M, Wilhelm M, Ranft U, Jöckel KH: Childhood social position and associations between environmental exposures and health outcomes. Int J Hyg Environ Health 212 (2): 146-156, 2009.
 

Sopjani M, Föller M, Haendeler J, Götz F, Lang F: Silver ion-induced suicidal erythrocyte death. J Appl Toxicol 29 (6): 531-536, 2009.
 

Eckers A, Klotz LO: Heavy metal ion-induced insulin-mimetic signalling. Redox Rep 14 (4): 141-146, 2009.
 

Esser C, Jux B: Small chemicals, bioactivation, and the immune system ? a fragile balance of i-tox and benefits? Chemistry & Biodiversity 6 (11): 2138-2143, 2009.
 

Krutmann J, Schroeder P: Role of mitochondria in photoageing of human skin: The defective powerhouse model. 
J Invest Dermatol Symp Proc 14 (1): 44-49, 2009.
 

Schnabel E, Sausenthaler S, Liese J, Herbarth O, Borte M, Schaaf B, Krämer U, von Berg A, Wichmann HE, Heinrich J; for the LISA-Study-Group: Hospital admission in children up to the age of 2 years. Eur J Pediatr 168 (8): 925-931, 2009.
 

Schnabel E, Sausenthaler S, Brockow I, Liese J, Herbarth O, Michael B, Schaaf B, Krämer U, von Berg A, Wichmann HE, Heinrich J; for the LISA Study Group: Burden of otitis media and pneumonia in children up to 6 years of age: results of the LISA birth cohort. Eur J Pediatr 168 (10): 1251-1257, 2009.
 

Brockow I, Zutavern A, Hoffmann U, Grübl A, von Berg A, Koletzko S, Filipiak B, Bauer CP, Wichmann HE, Reinhardt D, Berdel D, Krämer U, Heinrich J; GINIplus Study Group: Early allergic sensitizations and their relevance to atopic diseases in children aged 6 years: results of the GINI study. J Investig Allergol Clin Immunol 19 (3): 180-187, 2009.
 

Sausenthaler S, Rzehak P, Chen CM, Arck P, Bockelbrink A, Schäfer T, Schaaf B, Borte M, Herbarth O, Krämer U, von Berg A, Wichmann HE, Heinrich J; LISA Study Group: Stress-related maternal factors during pregnancy in relation to childhood eczema: results from the LISA Study. J Investig Allergol Clin Immunol 19 (6): 481-487, 2009.
 

Bhattacharya K, Davoren M, Boertz J, Schins RP, Hoffmann E, Dopp E: Titanium dioxide nanoparticles induce oxidative stress and DNA adduct formation but not DNA breakage in human lung cells. Part Fibre Toxicol 6 (1): 17, 2009.
 

Goergens A, Frericks M, Esser C: The AhR is only marginally involved in the anti-leukemic effects of its ligand curcumin. Anticancer Research 29 (11): 4657-4664, 2009.
 

Grether-Beck S, Krutmann J: Involment of lipid rafts and caveolins in UVA signaling. The Open Dermatology Journal 3: 153-159, 2009.
 

Herbert OC, Barnetson R, Weninger W, Krämer U, Behrendt H, Ring J: Western lifestyle and increased prevalence of atopic diseases. World Allergy Organization Journal 2: 130-137, 2009.
 

Jakob S, Altschmied J*, Haendeler J*: “Shping 2” different cellular localizations - a potential new player in aging processes. Aging 1, 664-668, 2009. (*equally contributed senior authors)
 

Koyanagi M, Iwasaki M, Haendeler J, Leitges M, Zeiher AM, Dimmeler S: Wnt5a increases cardiac gene expressions of cultured human circulating progenitor cells via a PKC delta activation. PLoS One 4(6): e5765, 2009.
 

Pluskota A, Horzowski E, Bossinger O, von Mikecz A: In Caenorhabditis elegans nanoparticle-bio-interactions become transparent: Silica-nanoparticles induce reproductive senescence. PLoS One 4 (8) e6622, 2009.
 

Seeger FH, Chen L, Spyridopoulos I, Altschmied J, Aicher A, Haendeler J: Downregulation of Ets rescues diabetes-induced reduction of endothelial progenitor cells. PLoS One 4 (2): e4529, 2009.
 

Schroeder P, Calles C, Krutmann J: Prevention of Infrared-A radiation mediated detrimental effects in human skin. Skin Therapy Letters 14 (5): 4-5, 2009.