Aktuelle Publikationen

Originalarbeiten

Masjosthusmann S, Becker D, Petzuch B, Klose J, Siebert C, Deenen R, Barenys M, Baumann J, Dach K, Tigges J, Hübenthal U, Köhrer K, Fritsche E: A transcriptome comparison of time-matched developing human, mouse and rat neural progenitor cells reveals human uniqueness. Toxicol Appl Pharmacol 2018. doi: 10.1016/j.taap.2018.05.009

Bühlmeier J, Harris C, Koletzko S, Lehmann I, Bauer CP, Schikowski T, von Berg A, Berdel D, Heinrich J, Hebebrand J, Föcker M, Standl M, Libuda L: Dietary acid load and mental health outcomes in children and adolescents: Results from the GINIplus and LISA birth cohort studies. Nutrients 2018 10(5): E582. doi: 10.3390/nu10050582

Mayerl S, Schmidt M, Doycheva D, Darras VM, Hüttner SS, Boelen A, Visser TJ, Kaether C, Heuer H, von Maltzahn J: Thyroid hormone transporters MCT8 and OATP1C1 control skeletal muscle regeneration. Stem Cell Rep 2018. doi: 10.1016/j.stemcr.2018.03.021

Kotz S, Kullmann M, Kalayda GV, Dyballa-Rukes N, Jaehde U, Metzger S: Optimized two-dimensional gel electrophoresis in an alkaline pH range improves the identification of intracellular CFDA-cisplatin-protein adducts in ovarian cancer cells. Electrophoresis 2018. doi: 10.1002/elps.201700377

Thacher JD, Gehring U, Gruzieva O, Standl M, Pershagen G, Bauer CP, Berdel D, Keller T, Koletzko S, Koppelman GH, Kull I, Lau S, Lehmann I, Maier D, Schikowski T, Wahn U, Wijga AH, Heinrich J, Bousquet J, Anto JM, von Berg A, Melén E, Smit HA, Keil T, Bergström A: Maternal smoking during pregnancy and early childhood and development of asthma and rhinoconjunctivitis - a MeDALL project. Environ Health Perspect 126(4): 047005, 2018. doi: 10.1289/EHP2738

Smith MP, Standl M, Berdel D, von Berg A, Bauer CP, Schikowski T, Koletzko S, Lehmann I, Krämer U, Heinrich J, Schulz H: Handgrip strength is associated with improved spirometry in adolescents. Plos One 13(4): e0194560, 2018. doi: 10.1371/journal.pone.0194560

Hüls A, Klümper C, MacIntyre EA, Brauer M, Melén E, Bauer M, Berdel D, Bergström A, Brunekreef B, Chan-Yeung M, Fuertes E, Gehring U, Gref A, Heinrich J, Standl M, Lehmann I, Kerkhof M, Koppelman GH, Kozyrskyj AL, Pershagen G, Carlsten C, Krämer U, Schikowski T; TAG Study Group: Atopic dermatitis: Interaction between genetic variants of GSTP1, TNF, TLR2, and TLR4 and air pollution in early life. Pediatr Allergy Immunol 2018. doi: 10.1111/pai.12903

Perkins TN, Peeters PM, Albrecht C, Schins RPF, Dentener MA, Mossman BT, Wouters EFM, Reynaert NL: Crystalline silica alters Sulfatase-1 expression in rat lungs which influences hyper-proliferative and fibrogenic effects in human lung epithelial cells. Toxicol Appl Pharmacol 348: 43-53, 2018. doi: 10.1016/j.taap.2018.04.011

Stöckmann D, Spannbrucker T, Ale-Agha N, Jakobs P, Goy C, Dyballa-Rukes N, Hornstein T, Kümper A, Kraegeloh A, Haendeler J, Unfried K: Non-canonical activation of the epidermal growth factor receptor by carbon nanoparticles. Nanomaterials 8(4): 267, 2018. doi: 10.3390/nano8040267

Lanzinger S, Rosenbauer J, Sugiri D, Schikowski T, Treiber B, Klee D, Rathmann W, Holl RW: Impact of long-term air pollution exposure on metabolic control in children and adolescents with type 1 diabetes: results from the DPV registry. Diabetologia 61(6): 1354-1361, 2018. doi: 10.1007/s00125-018-4580-8

Esser C, Haarmann-Stemmann T, Hochrath K, Schikowski T, Krutmann J: AHR and the issue of immunotoxicity. Curr Opinion Toxicol 10: 91-97, 2018. doi: 10.1016/j.cotox.2018.03.001

Nakamura M*, Haarmann-Stemmann T*, Krutmann J, Morita A: Alternative test models for skin aging research. Exp Dermatol 2018. doi: 10.1111/exd.13519

Lademann J, Knorr F, Patzelt A, Meinke MC, Richter H, Krutmann J, Rühl E, Doucet O: Laser scanning microscopic investigations of the decontamination of soot nanoparticles from the skin. Skin Pharmacol Physiol 31(2): 87-94, 2018. doi: 10.1159/000485900

Ermakova YG, Pak VV, Bogdanova YA, Kotlobay AA, Yampolsky IV, Shokhina AG, Panova AS, Marygin RA, Staroverov DB, Bilan DS, Sies H, Belousov VV: SypHer3s: a genetically encoded fluorescent ratiometric probe with enhanced brightness and an improved dynamic range. Chem Commun (Camb) 54(23): 2898-2901, 2018. doi: 10.1039/c7cc08740c

Bal-Price A, Hogberg HT, Crofton KM, Daneshian M, FitzGerald RE, Fritsche E, Heinonen T, Hougaard Bennekou S, Klima S, Piersma AH, Sachana M, Shafer TJ, Terron A, Monnet-Tschudi F, Viviani B, Waldmann T, Westerink RHS, Wilks MF, Witters H, Zurich MG, Leist M: Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity. ALTEX 2018. doi: 10.14573/altex.1712081

Fritsche E, Grandjean P, Crofton KM, Aschner M, Goldberg A, Heinonen T, Hessel EVS, Hogberg H, Bennekou SH, Lein PJ, Leist M, Mundy WR, Paparella M, Piersma AH, Sachana M, Schmuck G, Solecki R, Terron A, Monnet-Tschudi F, Wilks MF, Witters H, Zurich MG, Bal-Price A: Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes. Toxicol Appl Pharmacol 2018. doi: 10.1016/j.taap.2018.02.004

Baker N, Boobis A, Burgoon L, Carney E, Currie R, Fritsche E, Knudsen T, Laffont M, Piersma AH, Poole A, Schneider S, Daston G: Building a developmental toxicity ontology. Birth Defects Res Part B-Dev Reprod Toxicol 110(6): 502-518, 2018. doi: 10.1002/bdr2.1189

Harder L, Dudazy-Gralla S, Müller-Fielitz H, Hjerling Leffler J, Vennström B, Heuer H, Mittag J: Maternal thyroid hormone is required for parvalbumin neurone development in the anterior hypothalamic area. J Neuroendocrinol 30(3): e12573, 2018. doi: 10.1111/jne.12573

Liu W, Pan X, Vierkötter A, Guo Q, Wang X, Wang Q, Seité S, Moyal D, Schikowski T, Krutmann J: A time-series study of the effect of air pollution on outpatient visits for acne vulgaris in Beijing. Skin Pharmacol Physiol 31: 107-113, 2018. doi: 10.1159/000484482

Hüls A, Vierkötter A, Sugiri D, Abramson MJ, Ranft U, Krämer U, Schikowski T: The role of air pollution and lung function on cognitive impairment. Eur Respir J 51: 1701963, 2018. doi: 10.1183/13993003.01963-2017

Ispanixtlahuatl-Meráz O, Schins RPF, Chirino YI: Cell type specific cytoskeleton disruption induced by engineered nanoparticles. Environ Sci Nano 5: 228-245, 2018. doi: 10.1039/C7EN00704C

Piechulek A, von Mikecz A: Life span-resolved nanotoxicology enables identification of age-associated neuromuscular vulnerabilities in the nematode Caenorhabditis elegans. Environ Pollut 233: 1095-1103, 2018. doi: 10.1016/j.envpol.2017.10.012

Filipiak-Pittroff B, Koletzko S, Krämer U, Standl M, Bauer C-P, Berdel D, von Berg A: Full breastfeeding and allergies from infancy until adolescence in the GINIplus cohort. Pediatr Allergy Immunol 29(1): 96-101, 2018. doi: 10.1111/pai.12798

Kassahun H, SenGupta T, Schiavi A, Maglioni S, Skjeldam HK, Arczewska K, Brockway NL, Estes S, Eide L, Ventura N, Nilsen H: Constitutive MAP-kinase activation suppresses germline apoptosis in NTH-1 DNA glycosylase deficient C. elegans. DNA Repair (Amst) 61: 46-55, 2018. doi: 10.1016/j.dnarep.2017.11.009

Tischer C, Dadvand P, Basagana X, Fuertes E, Bergström A, Gruzieva O, Melen E, Berdel D, Heinrich J, Koletzko S, Markevych I, Standl M, Sugiri D, Cirugeda L, Estarlich M, Fernández-Somoano A, Ferrero A, Ibarlueza J, Lertxundi A, Tardón A, Sunyer J, Anto JM: Urban upbringing and childhood respiratory and allergic conditions: A multi-country holistic study. Environ Res 161: 276-283, 2018. doi: 10.1016/j.envres.2017.11.013

Proquin H, Jetten MJ, Jonkhout MCM, Garduño-Balderas LG, Briedé JJ, de Kok TM, Chirino YI, van Loveren H: Gene expression profiling in colon of mice exposed to food additive titanium dioxide (E171). Food Chem Toxicol 111: 153-165, 2018. doi: 10.1016/j.fct.2017.11.011

Fülle L, Steiner N, Funke M, Gondorf F, Pfeiffer F, Siegl J, Opitz FV, Haßel SK, Erazo AB, Schanz O, Stunden HJ, Blank M, Gröber C, Händler K, Beyer M, Weighardt H, Latz E, Schultze JL, Mayer G, Förster I: RNA aptamers recognizing murine CCL17 inhibit T cell chemotaxis and reduce contact hypersensitivity in vivo. Mol Ther 26(1): 95-104, 2018. doi: 10.1016/j.ymthe.2017.10.005

Hendgen-Cotta UB, Esfeld S, Jastrow H, Totzeck M, Altschmied J, Goy C, Haendeler J, Winterhager E, Rassaf T: Mouse cardiac mitochondria do not separate in subsarcolemmal and interfibrillar subpopulations. Mitochondrion 38: 1-5, 2018. doi: 10.1016/j.mito.2017.07.005

Übersichtsarbeiten, Buchbeiträge u.a.

Schneider A, Rückerl R, Standl M, Markevych I, Hoffmann B, Moebus S, Jöckel KH, Weber A, Herr C, Heißenhuber A, Nennstiel-Ratzel U, Heinze S, Schulz C, Kolossa-Gehring M, Niemann H, Gößwald A, Schikowski T, Hüls A, Sugiri D, Peters A: Epidemiological studies with environmental relevance in Germany. Bundesgesundheitsblatt-Gesund 2018. doi: 10.1007/s00103-018-2740-0

Mescher M, Haarmann-Stemmann T: Modulation of CYP1A1 metabolism: From adverse health effects to chemoprevention and therapeutic options. Pharmacol Ther 2018. doi: 10.1016/j.pharmthera.2018.02.012

Diepgen TL, Kresken J, Krutmann J, Merk HF, Senger E, Surber C, Szeimies RM; GD Task Force "Licht.Hautkrebs.Prävention" of the Society for Dermopharmacy: Commentary on the "Evidence- and Consensus-Based (S3) Guidelines for the Treatment of Actinic Keratosis" published by the International League of Dermatological Societies in cooperation with the European Dermatology Forum. Skin Pharmacol Physiol 31(3): 144-146, 2018. doi: 10.1159/000486687

Heinrich J, Schikowski T: COPD patients as vulnerable subpopulation for exposure to ambient air pollution. Curr Environ Health Rep 5(1): 70-76, 2018. doi: 10.1007/s40572-018-0178-z

von Mikecz A: Lifetime eco-nanotoxicology in an adult organism: where and when is the invertebrate C. elegans vulnerable? Environ Sci-Nano 5: 616-622, 2018. doi: 10.1039/C7EN01061C

Krutmann J, Sondenheimer K, Grether-Beck S, Haarmann-Stemmann T: Combined, simultaneous exposure to radiation within and beyond the UV spectrum: A novel approach to better understand skin damage by natural sunlight. In: Merk J, Krutmann J (Eds.): Environment and skin. Springer International Publishing, Switzerland, 2018. ISBN: 9783319431000, pp 11-16.

Pavez Loriè E, Stark H-J, Berning M, Boukamp P: Skin squamous cell carcinoma models: The role in combating the disease. In: Marques A, Pirraco RP, Cerqueria MT, Reis RL (Eds.): Skin tissue models. Elsevier, London, UK. ISBN 9780128105450,  pp 151-173.

Heiss C, Spyridopoulos I, Haendeler J: Interventions to slow cardiovascular aging: Dietary restriction, drugs and novel molecules. Exp Gerontol 2018. doi: 10.1016/j.exger.2017.06.015

Reinke H, Asher G: Liver Size: Waning by day, waxing by night. Hepatology 67(1): 441-443, 2018. doi: 10.1002/hep.29506