Aktuelle Publikationen

Originalarbeiten

Heiseke AF, Faul AC, Lehr HA, Förster I, Schmid RM, Krug A, Reindl W: CCL17 promotes intestinal inflammation in mice and counteracts regulatory T cell-mediated protection from colitis. Gastroenterology 142(2): 335-345, 2012. [pubmed]
 

Poppensieker K, Otte DM, Schürmann B, Limmer A, Dresing P, Drews E, Schumak B, Klotz L, Raasch J, Mildner A, Waisman A, Scheu S, Knolle P, Förster I, Prinz M, Maier W, Zimmer A, Alferink J: CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells. Proc Natl Acad Sci USA 109(10): 3897-3902, 2012. [pubmed]
 

Koletzko S, Filipiak-Pittroff B, Koletzko B, von Berg A, Krämer U, Berdel D, Heinrich J; German Infant Nutritional Intervention study group: No reason to change the current guidelines on allergy prevention. J Allergy Clin Immunol 129(1): 262-262, 2012.
 

Winter C, Pfister D, Busch J, Bingol C, Ranft U, Schrader M, Dieckmann KP,  Heidenreich A, Albers P: Residual tumor size and IGCCCG risk classification predict additional vascular procedures in patients with germ cell tumors and residual tumor resection: A multicenter analysis of the German testicular cancer study group. Eur Urol 61(2): 403-409, 2012. [pubmed]
 

Flexeder C, Thiering E, Brüske I, Koletzko S, Bauer CP, Wichmann HE, Mansmann U, von Berg A, Berdel D, Krämer U, Schaaf B, Lehmann I, Herbarth O, Heinrich J; for the GINIplus and LISAplus Study Group: Growth velocity during infancy and onset of asthma in school-aged children. Allergy 67(2): 257-264, 2012. [pubmed]
 

Jarvis D, Newson R, Lötvall J, Hastan D, Tomassen P, Keil T, Gjomarkaj M, Forsberg B, Gunnbjörnsdóttir M, Minov J, Brozek G, Dahlen S, Toskala E, Kowalski ML, Olze H, Howarth PH, Krämer U, Baelum J, Loureiro C, Kaspar L, Bousquet PJ, Bousquet J, Bachert C, Fokkens W, Burney P. Asthma in adults and its association with chronic rhinosinusitis: The GA2LEN survey in Europe. Allergy 67(1): 91-98, 2012. [pubmed]
 

Standl M, Sausenthaler S, Lattka E, Koletzko S, Bauer CP, Wichmann HE, von Berg A, Berdel D, Krämer U, Schaaf B, Lehmann I, Herbarth O, Klopp N, Koletzko B, Heinrich J; for the GINIplus and LISAplus Study Group: FADS gene cluster modulates the effect of breastfeeding on asthma. Results from the GINIplus and LISAplus studies. Allergy 67(1): 83-90, 2012. [pubmed]
 

Grether-Beck S, Felsner I, Brenden B, Kohne Z, Majora M, Marini A, Jaenicke J, Rodriguez-Martin M, Trullas C, Hupe M, Elias PE, Krutmann J: Urea uptake enhances barrier function and antimicrobial defense in humans by regulating epidermal gene expression. J Invest Dermatol 132(6): 1561-1572, 2012. [pubmed]
 

Haarmann-Stemmann T, Abel J, Fritsche E, Krutmann J: The AhR-Nrf2 Pathway in Keratinocytes: On the Road to Chemoprevention? J Invest Dermatol 132 (1): 7-9, 2012. [pubmed]
 

Vierkötter A, Krämer U, Sugiri D, Morita A, Yamamoto A, Kaneko N, Matsui M, Krutmann J: Development of lentigines in German and Japanese women correlates with variants in the SLC45A2 gene (Letter to the Editor). J Invest Dermatol 132(3): 733-736, 2012.
 

Govarts E, Nieuwenhuijsen M, Schoeters G, Ballester F, Bloemen K, de Boer M, Chevrier C, Eggesbø M, Guxens M, Krämer U, Legler J, Martinez D, Palkovicova L, Patelarou E, Ranft U, Rautio A, Skaalum Petersen M, Slama R, Stigum H, Toft G, Trnovec T, Vandentorren S, Weihe P, Weisglas Kuperus N, Wilhelm M, Wittsiepe J, Bonde JP, and OBELIX/ENRIECO: Prenatal Exposure to Polychlorinated Biphenyls (PCB) and Dichlorodiphenyldichloroethylene (DDE) and Birth Weight: A Meta-analysis within 12 European Birth Cohorts. Environ Health Perspect 120(2): 162-170, 2012. [pubmed]
 

Hoffmann B, Luttmann-Gibson H, Cohen A, Zanobetti A, de Souza C, Foley C, Suh HH, Coull BA, Schwartz J, Mittleman M, Stone P, Horton E, Gold DR: Opposing effects of particle pollution, ozone and ambient temperature on arterial blood pressure. Environmental Health Perspectives 120(2): 241-246, 2012. [pubmed]
 

Sørensen M, Hoffmann B, Hvidberg M, Ketzel M, Jensen SS, Andersen ZJ, Tjønneland A, Overvad K, Raaschou-Nielsen 0: Long-term exposure to traffic-related air oollution, blood pressure and self-reported hypertension in a Danish cohort. Environ Health Perspect 120(3): 418-424, 2012. [pubmed]
 

Gais P, Reim D, Jusek G, Rossmann-Bloeck T, Weighardt H, Pfeffer K, Altmayr F, Janssen KP, Holzmann B: Cutting edge: divergent cell-specific functions of MyD88 for inflammatory responses and organ injury in septic peritonitis. J Immunol 2012, in press. (pubmed]
 

Shao D, Oka S, Brady CD, Haendeler J, Eaton P, Sadoshima J: Redox modification of cell signaling in the cardiovascular system. J Mol Cell Cardiol 52(3): 550-558, 2012. [pubmed]
 

Röck K, Meusch M, Fuchs N, Tigges J, Zipper P, Fritsche E, Krutmann J, Homey B, Reifenberger J, Fischer JW: Estradiol protects the dermal hyaluronan/versican matrix during photoaging by release of epidermal growth factor from keratinocytes. J Biol Chem 2012, in press. [pubmed]
 

Bhattacharya K, Hoffmann E, Schins RPF, Boertz J, Prantl EM, Alink GM, Byrne HJ, Kuhlbusch TAJ,Rahman Q, Wiggers H, Schulz C, Dopp E: Comparison of micro- and nanoscale Fe+3-containing (hematite) particles for their toxicological properties in human lung cells in vitro. Toxicol Sci 126(1): 173-182, 2012. [pubmed]
 

Köhler T, Reizis B, Johnson RS, Weighardt H, Förster I: Influence of hypoxia-inducible factor 1α on dendritic cell differentiation and migration. Eur J Immunol 42(5): 1226-1236, 2012. [pubmed]
 

Boots AW, Gerloff K, Bartholome R, Van Berlo D, Ledermann K, Haenen GR, Bast A, Van Schooten FJ, Albrecht C, Schins RPF: Neutrophils augment LPS-mediated pro-inflammatory signaling in human lung epithelial cells. Biochimica et Biophysica Acta – Molecular Cell Research 2012, in press.
 

Stahl W, Sies H: Photoprotection by dietary carotenoids: Concept, mechanisms, evidence and future development. Mol Nutr Food Res 55, xxx-xxx, 2012, in press. [pubmed]
 

Götz C, Pfeiffer R, Tigges T, Ruwiedel K, Hübenthal U, Merk HF, Krutmann J, Edwards RJ, Abel J, Goebel C, Hewitt N, Fritsche E: Xenobiotic metabolism capacities of human skin in comparison with a 3D-epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: phase II enzymes. Exp Dermatol 21(5): 364-369, 2012. [pubmed]
 

Götz C, Pfeiffer R, Tigges T, Blatz V, Jäckh C, Freytag EM, Fabian E, Landsiedel R, Merk HF, Krutmann J, Edwards RJ, Pease C, Goebel C, Hewitt N, Fritsche E: Xenobiotic metabolism capacities of human skin in comparison with a 3D-epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: activating enzymes (phase I). Exp Dermatol 21(5): 358-363, 2012. [pubmed]
 

Marini A, Farwick M, Grether-Beck S, Brenden H, Felsner I, Jaenicke T, Weber M, Schild J, Maczkiewitz U, Köhler T, Bonfigli A, Pagani V, Krutmann J: Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects. Exp Dermatol 21(2): 140-146, 2012. [pubmed]
 

Gerloff K, Fenoglio I Carella E, Kolling J, Albrecht C, Boots A, Förster I, Schins R: Distinctive toxicity of TiO2 rutile/anatase mixed phases nanoparticles on Caco-2 cells. Chemical Research in Toxicology 2012, in press. [pubmed]
 

Gerloff K, Pereira DIA, Faria N, Boots AW, Kolling J, Förster I, Albrecht C, Powell JJ, Schins RPF. Influence of simulated gastro-intestinal conditions on particle-induced cytotoxicity and interleukin-8 regulation in differentiated and undifferentiated Caco-2 cells. Nanotoxicology 2012, in press.
 

Büchner N, Ale-Agha N, Jakob S, Sydlik U, Kunze K, Unfried K, Altschmied J, Haendeler J: Unhealthy diet and ultrafine carbon black particles induce senescence and disease associated phenotypic changes. Exp Gerontol 2012, in press. [pubmed]
 

De Spirt S, Sies H, Tronnier H, Heinrich U: An encapsulated fruit and vegetable juice concentrate increases skin microcirculation in healthy women. Skin Pharmacol Physiol 25 (1), 2-8, 2012. [pubmed]
 

Casas L, Tiesler C, Thiering E, Brüske I, Koletzko S, Bauer CP, Wichmann HE, von Berg A, Berdel D, Krämer U, Schaaf B, Lehmann I, Herbarth O, Sunyer J, Heinrich J; for the GINIplus and LISAplus Study Group: Indoor factors and behavioural problems in children: The GINIplus and LISAplus birth cohort studies. Int J Hyg Environ Health 2012, in press. [pubmed]
 

Marini A*, Grether-Beck S*, Jaenicke T, Weber M, Burki C, Formann P, Brenden H, Schönlau F, Krutmann J: Pycnogenol® effects on skin elasticity and hydration coincide with increased gene expressions of collagen type I and hyaluronic acid synthase in women. Skin Pharmacology & Physiology 25(2): 86-92, 2012. (*equal contribution) [pubmed]
 

Goetz C, Hewitt NJ, Jermann E, Tigges T, Kohne Z, Huebenthal U, Krutmann J, Merk HF, Fritsche E: Effects of the genotoxic compounds, benzo[a]pyrene and cyclophosphamide on phase 1 and 2 activities in EpiDerm™ models. Xenobiotica 42(6): 526-537, 2012. [pubmed]
 

Wilhelmi V, Fischer U, van Berlo D, Schulze-Osthoff K, Schins RPF, Albrecht C: Evaluation of apoptosis induced by nanoparticles and fine particles in RAW 264.7 macrophages: facts and artefacts. Toxicology in vitro 26(2): 323-334, 2012. [pubmed]
 

Casas L, Tischer C, Tiesler C, Brüske I, Koletzko S, Bauer CP, Wichmann HE, von Berg A, Berdel D, Krämer U, Schaaf B, Lehmann I, Herbarth O, Heinrich J; for the GINIplus LISAplus Study Group: Association of gas cooking with children's respiratory health: results from GINIplus and LISAplus birth cohort studies. Indoor Air 2012, in press. [pubmed]
 

Krämer U, Vierkötter A, Schikowski T, Sugiri D, Brüning T, Raulf-Heimsoth M: Prävalenz und Inzidenz allergischer Erkrankungen bei Älteren – Ergebnisse der Kohortenstudie SALIA. Allergologie 35: 2012, in press.
 

Übersichtsarbeiten, Buchbeiträge u.a.

Cramer C, Link E, Koletzko S, Lehmann I, Herbarth O, Borte M, Schaaf B, Heinrich J, Wichmann HE, Bauer CP, von Berg A, Berdel D, Behrendt H, Krämer U, for the GINIplus and LISAplus Study Group: The hygiene hypothesis does not apply to atopic eczema in childhood. In: Ring J, Darsow U, Behrendt H (eds): Chemical immunology and allergy. New Trends in Allergy and Atopic Eczema, vol 96. Basel, Karger 2012, pp. 15-23 [pubmed]
 

Eckers A, Altschmied J, Haendeler J: Oxidativer Stress im Endothel und bei Diabetes Typ 2. Z Gerontol Geriatr 45(2): 90-94, 2012. [pubmed]
 

Esser C: Biology of the aryl hydrocarbon receptor: report of an international and interdisciplinary conference. Arch Toxicol 2012, in press. [pubmed]
 

Genuneit J, Grabenhenrich L, Krämer U, Cramer C, Schlaud M, für die Arbeitsgruppe „Epidemiologie allergischer und dermatologischer Erkrankungen“ der Deutschen Gesellschaft für Epidemiologie: Epidemiologische Forschung zu allergischen Erkrankungen in Deutschland: eine Chronologie. Allergologie 35 (1), 3-10, 2012.
 

Haendeler J, Eckers A, Lukosz M, Unfried K, Altschmied J: Endothelial NADPH oxidase 2 – when does it matter in atherosclerosis? Cardiovasc Res 94(1):1-2, 2012.
 

Heinrich J, Brüske I, Cramer C, Hoffmann U, Schnappinger M, Schaaf B, von Berg A, Berdel D, Krämer U, Lehmann I, Herbarth O, Borte M, Grübl A, Bauer CP, Beckmann C, Behrendt H, Ring J, Koletzko S: GINIplus und LISAplus. Design und ausgewählte Ergebnisse zweier deutscher Geburtskohorten zum natürlichen Verlauf atopischer Erkrankungen sowie deren Determinanten. Allergologie 35 (1): 20-31, 2012.
 

Kochevar I, Taylor R, Krutmann J: Fundamentals of Cutaneous Photobiology and Photoimmunology. In: Fitzpatrick´s Dermatology in General Medicine (Wolff K, Goldsmith L.A, Katz S, Gilchrest B, Paller AS, Leffell DJ eds) eighth edition, McGraw-Hill, New York, pp 1031-1049, 2012.
 

Krutmann J: Pre- and probiotics for human skin. Clin Plast Surg 39(1): 59-64, 2012. [pubmed]
 

Krutmann J, Morita A, Chung JH: Sun exposure – what molecular photodermatology tells us about its good and bad sides. J Invest Dermatol 132 (3 Pt 2): 976-984, 2012. [pubmed]
 

Mang R, Stege H, Krutmann J: Mechanisms in phototoxic and photoallergic reactions. In: Textbook of Contact Dermatitis, 5th ed, (Menné T, Frosch P, eds), Springer Berlin, Heidelberg 2012 (in press)
 

Schins RPF, Albrecht C, Gerloff K, Van Berlo D: Genotoxicity of carbon nanotubes. In: (Donaldson K, Poland C, Duffin R, Eds.) The Inhalation Toxicology of Carbon Nanotubes. Cambridge University Press, UK, 2012, in press
 

Van Berlo D, Hullmann M, Schins RPF: Toxicology of ambient particulate matter. In: (Luch A, Ed.) Molecular, Clinical and Environmental Toxicology. Volume 3. Molecular Toxicology Series: Experientia Supplementum, Birkhäuser Basel, 2012, in press.
 

von Berg A, Filipiak-Pittroff B, Krämer U, Link E, Heinrich J, Koletzko S, Grübl A, Hoffmann U, Beckmann C, Reinhardt D, Bauer CP, Wichmann HE, Berdel D: Die German Infant Nutritional Intervention Study (GINI) zur präventiven Wirkung von Hydrlysatnahrungen bei Kindern mit Allergierisiko. Design und ausgewählte Ergebnisse. Allergologie 35 (1): 32-43, 2012.
 

Vrijheid M, Casas M, Bergström A, Carmichael A, Cordier S, Eggesbø M, Eller E, Fantini MP, Fernández MF, Fernández-Somoano A, Gehring U, Grazuleviciene R, Hohmann C, Karvonen AM, Keil T, Kogevinas M, Koppen G, Krämer U, Kuehni C, Magnus P, Majewska R, Andersen AM, Patelarou E, Petersen MS, Pierik FH, Polanska K, Porta D, Richiardi L, Santos AC, Slama R, Sram RJ, Thijs C, Tischer C, Toft G, Trnovec T, Vandentorren S, Vrijkotte TG, Wilhelm M, Wright J, Nieuwenhuijsen M: European Birth Cohorts for Environmental Health Research. Environ Health Perspect 120(1): 29-37, 2012. [pubmed]