Aktuelle Publikationen

Originalarbeiten

Shebaby WN, Mroueh MA, Boukamp P, Ri RI, Bodman-Smith K, El-Sibai M, Daher CF: Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer. BMC Complement Altern Med 17(1): 36, 2017. doi: 10.1186/s12906-016-1531-0

Markevych I, Maier W, Fuertes E, Lehmann I, von Berg A, Bauer CP, Koletzko S, Berdel D, Sugiri D, Standl M, Heinrich J: Neighbourhood greenness and income of occupants in four German areas: GINIplus and LISAplus. Urban For Urban Green 21: 88-95, 2017. doi: 10.1016/j.ufug.2016.11.011

Aschner M, Ceccatelli S, Daneshian M, Fritsche E, Hasiwa N, Hartung T, Hogberg HT, Leist M, Li A, Mundi WR, Padilla S, Piersma AH, Bal-Price A, Seiler A, Westerink RH, Zimmer B, Lein PJ: Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use. ALTEX 34(1): 49-74, 2017. doi: 10.14573/altex.1604201

Thongkam W*, Gerloff K*, van Berlo D, Albrecht C, Schins FPR: Oxidant generation, DNA damage and cytotoxicity by a panel of engineered nanomaterials in three different human epithelial cell lines. Mutagenesis 32(1): 105-115, 2017. doi: 10.1093/mutage/gew056 (* equal contribution)

Barenys M, Gassmann K, Baksmeier C, Heinz S, Reverte I, Schmuck M, Temme T, Bendt F, Zschauer TC, Rockel TD, Unfried K, Wätjen W, Sundaram SM, Heuer H, Colomina MT, Fritsche E: Epigallocatechin gallate (EGCG) inhibits adhesion and migration of neural progenitor cells in vitro. Arch Toxicol 91(2): 827-837, 2017. doi: 10.​1007/​s00204-016-1709-8

Gao W*, Tan J*, Hüls A*, Ding A, Liu Y, Matsui M, Vierkötter A, Krutmann J#, Schikowski T#, Jin L#, Wang S#: Genetic variants associated with skin aging in Chinese Han population. J Dermatol Sci 2016. doi: 10.1016/j.jdermsci.2016.12.017 (* equal contribution; # Co-senior authors)

Zhang M, Li B, Wu S, Tan J, Yang Y, Marini A, Vierkötter A, Zhang J, Li H, Schikowski T, Jin L, Krutmann J, Wang S: A genome-wide association study of basal transepidermal water loss finds variants at 9q34.3 to be associated with skin barrier function. J Invest Dermatol 2016. doi: 10.1016/j.jid.2016.11.030

Standl M, Tesch F, Baurecht H, Rodríguez E, Müller-Nurasyid M, Gieger C, Peters A, Wang-Sattler R, Prehn C, Adamski J, Kronenberg F, Schulz H, Koletzko S, Schikowski T, von Berg A, Lehmann I, Berdel D, Heinrich J, Schmitt J, Weidinger S: Association of atopic dermatitis with cardiovascular risk factors and diseases. J Invest Dermatol 2016. doi: 10.1016/j.jid.2016.11.031

Zhang M, Wu S, Zhang J, Yang Y, Tan J, Liu Y, Guan H, Tang K, Krutmann J, Xu S, Jin L, Guan Y, Li H, Wang S: Large-scale genome-wide scans do not support petaloid toenail as a Mendelian trait. J Genet Genomics 43(12): 702-704, 2016. doi: 10.1016/j.jgg.2016.10.003

Schmuck MR, Temme T, Dach K, de Boer D, Barenys M, Bendt F, Mosig A, Fritsche E: Omnisphero: a high-content image analysis (HCA) approach for phenotypic developmental neurotoxicity (DNT) screenings of organoid neurosphere cultures in vitro. Arch Toxicol 2016. doi: 10.1007/s00204-016-1852-2

Dyballa-Rukes N*, Jakobs P*, Eckers A*, Ale-Agha N, Serbulea V, Aufenvenne K, Zschauer TC, Rabanter LL, Jakob S, von Ameln F, Eckermann O, Leitinger N, Goy C, Altschmied J#, Haendeler J#: The anti-apoptotic properties of APEX1 in the endothelium require the first twenty amino acids and converge on Thioredoxin-1. Antioxid Redox Signal 2016. doi: 10.1089/ars.2016.6799 (*,# equal contribution)

Kohlgrüber S, Upadhye A, Dyballa-Rukes N, McNamara CA, Altschmied J: Regulation of transcription factors by reactive oxygen species and nitric oxide in vascular physiology and pathology. Antioxid Redox Signal 2016. doi: 10.1089/ars.2016.6946

Jakobs P*, Serbulea V*, Leitinger N, Eckers A#, Haendeler J#: Nuclear factor (erythroid-derived 2)-like 2 and Thioredoxin-1 in atherosclerosis and ischemia/reperfusion injury in the heart. Antioxid Redox Signal 2016. doi: 10.1089/ars.2016.6795 (*,# equal contribution)

Li H, Frappart L, Moll J, Winkler A, Kroll T, Hamann J, Kufferath I, Groth M, Taudien S, Schütte M, Yaspo ML, Heuer H, Lange BM, Platzer M, Zatloukal K, Herrlich P, Ploubidou A: Impaired planar germ cell division in the testis, caused by dissociation of RHAMM from the spindle, results in hypofertility and seminoma. Cancer Res 76(21): 6382-6395, 2016. doi: 10.1158/0008-5472.CAN-16-0179

Fuertes E, Standl M, Forns J, Berdel D, Garcia-Aymerich J, Markevych I, Schulte-Koerne G, Sugiri D, Schikowski T, Tiesler CM, Heinrich J: Traffic-related air pollution and hyperactivity/inattention, dyslexia and dyscalculia in adolescents of the German GINIplus and LISAplus birth cohorts. Environ Int 97: 85-92. doi: 10.1016/j.envint.2016.10.017

Cinotti E, Perrot JL, Labeille B, Biron AC, Vierkötter A, Heusèle C, Nizard C, Schnebert S, Barthelemy JC, Cambazard F: Skin tumours and skin aging in 209 French elderly people: the PROOF study. Eur J Dermatol 26(5): 470-476, 2016. doi: 10.1684/ejd.2016.2838

Unfried K, Krämer U, Sydlik U, Autengruber A, Bilstein A, Stolz S, Marini A, Schikowski T, Keymel S, Krutmann J: Reduction of neutrophilic lung inflammation by inhalation of the compatible solute ectoine: a randomized trial with elderly individuals. Int J Chronic Obstr Pulm Dis 11(1): 2573-2583, 2016. doi: 10.2147/COPD.S115061

Haas K, Weighardt H, Deenen R, Köhrer K, Clausen B, Zahner S, Boukamp P, Bloch W, Krutmann J, Esser C: Aryl hydrocarbon receptor in keratinocytes is essential for murine skin barrier integrity. J Invest Dermatol 136(11): 2260-2269, 2016. doi: 10.1016/j.jid.2016.06.627

Ingenwerth M, Noichl E, Stahr A, Korf HW, Reinke H, von Gall C: Heat shock factor 1 deficiency affects systemic body temperature regulation. Neuroendocrinology 103(5): 605-615, 2016. doi: 10.1159/000441947

Fehsel K, Schikowski T, Jänner M, Hüls A, Voussoughi M, Schulte T, Vierkötter A, Teichert T, Herder C, Sugiri D, Krämer U, Luckhaus C: Estrogen receptor beta polymorphisms and cognitive performance in women: associations and modifications by genetic and environmental influences. J Neural Transm (Vienna) 123(12): 1369-1379, 2016. doi: 10.1007/s00702-016-1620-8

Grether-Beck S, Marini A, Jaenicke T, Stahl W, Krutmann J: Molecular evidence that oral supplementation with lycopene or lutein protects human skin against ultraviolet radiation: Results from a double-blinded, placebo-controlled, cross-over study. Br J Dermatol 2016. doi: 10.1111/bjd.15080

Kalfalah F, Janke L, Schiavi A, Tigges J, Ix A, Ventura N, Boege F, Reinke H: Crosstalk of clock gene expression and autophagy in aging. Aging (Albany NY) 8(9): 1876-1895, 2016. doi: 10.18632/aging.101018

Markevych I, Standl M, Sugiri D, Harris C, Maier W, Berdel D, Heinrich J: Residential greenness and blood lipids in children: A longitudinal analysis in GINIplus and LISAplus. Short communication. Environ Res 151: 168-173, 2016. doi: 10.1016/j.envres.2016.07.037

Wu S, Tan J, Yang Y, Peng Q, Zhang M, Li J, Lu D, Liu Y, Lou H, Feng Q, Lu Y, Guan Y, Zhang Z, Jiao Y, Sabeti P, Krutmann J, Tang K, Jin L, Xu S, Wang S: Genome-wide scans reveal variants at EDAR predominantly affecting hair straightness in Han Chinese and Uyghur populations. Hum Genet 135(11): 1279-1286, 2016. doi: 10.1007/s00439-016-1718-y

Fehrenbach S, Novak D, Bernhardt M, Larribere L, Boukamp P, Umansky V, Utikal J: Loss of tumorigenic potential upon transdifferentiation from keratinocytic into melanocytic lineage. Sci Rep 6: 28891, 2016. doi: 10.1038/srep28891

de Hoogh K, Gulliver J, Donkelaar AV, Martin RV, Marshall JD, Bechle MJ, Cesaroni G, Pradas MC, Dedele A, Eeftens M, Forsberg B, Galassi C, Heinrich J, Hoffmann B, Jacquemin B, Katsouyanni K, Korek M, Künzli N, Lindley SJ, Lepeule J, Meleux F, de Nazelle A, Nieuwenhuijsen M, Nystad W, Raaschou-Nielsen O, Peters A, Peuch VH, Rouil L, Udvardy O, Slama R, Stempfelet M, Stephanou EG, Tsai MY, Yli-Tuomi T, Weinmayr G, Brunekreef B, Vienneau D, Hoek G: Development of West-European PM2.5 and NO2 land use regression models incorporating satellite-derived and chemical transport modelling data. Environ Res 151: 1-10, 2016. doi: 10.1016/j.envres.2016.07.005

Hüls A, Krämer U, Gappa M, Müller-Brandes C, Schikowski T, von Berg A, Hoffmann B, Schuster A, Wisbauer M, Flexeder C, Heinrich J, Schulz H, Berdel D: Age dependency of GLI reference values compared with paediatric lung function data in two German studies (GINIplus and LUNOKID). Plos One 11(7): e0159678. doi: 10.1371/journal.pone.0159678

Berg J, Mahmoudjanlou Y, Duscha A, Massa M, Thöne J, Esser C, Gold R, Haghikia A: The immunomodulatory effect of laquinimod in CNS autoimmunity is mediated by the aryl hydrocarbon receptor. J Neuroimmunol 298: 9-15, 2016. doi: 10.1016/j.jneuroim.2016.06.003

Hennig F, Sugiri D, Tzivian L, Fuks K, Moebus S, Jöckel K-H, Vienneau D, Kuhlbusch TAJ, de Hoogh K, Memmesheimer M, Jakobs H, Quass U, Hoffmann B: Comparison of land-use regression modeling with dispersion and chemistry transport modeling to assign air pollution concentrations within the Ruhr area. Atmosphere 7(3): 48, 2016. doi: 10.3390/atmos7030048

Hüls A, Krämer U, Stolz S, Hennig F, Hoffmann B, Ickstadt K, Vierkötter A, Schikowski T: Applicability of the global lung initiative 2012 reference values for spirometry for longitudinal data of elderly women. Plos One 11(6): e0157569, 2016. doi: 10.1371/journal.pone.0157569

de Vries EM, Nagel S, Haenold R, Sundaram SM, Pfrieger FW, Fliers E, Heuer H, Boelen A: The role of hypothalamic NF-κB signaling in the response of the HPT-axis to acute inflammation in female mice. Endocrinology 157(7): 2947-2956, 2016. doi: 10.1210/en.2016-1027

Vierkötter A*, Hüls A*, Yamamoto A, Stolz S, Krämer U, Matsui MS, Morita A, Wang S, Li Z, Jin L, Krutmann J*, Schikowski T*: Extrinsic skin aging in German, Chinese and Japanese women manifests differently in all three groups depending on ethnic background, age and anatomical site. J Dermatol Sci 83(3): 219-225, 2016. doi: 10.1016/j.jdermsci.2016.05.011 (* equal contribution)

Brandstätter O*, Schanz O*, Vorac J*, König J, Mori T, Maruyama T, Korkowski M, Haarmann-Stemmann T, von Smolinski D, Schultze JL, Abel J, Esser C, Takeyama H, Weighardt H*, Förster I*: Balancing intestinal and systemic inflammation through cell typespecific expression of the aryl hydrocarbon receptor repressor. Sci Rep 6: 26091, 2016. doi: 10.1038/srep26091 (* equal contribution)

Curjuric I, Imboden M, Bridevaux PO, Gerbase MW, Haun M, Keidel D, Kumar A, Pons M, Rochat T, Schikowski T, Schindler C, von Eckardstein A, Kronenberg F, Probst-Hensch NM: Common SIRT1 variants modify the effect of abdominal adipose tissue on aging-related lung function decline. Age 38(3): 52, 2016. doi: 10.1007/s11357-016-9917-y

Abramson MJ, Schindler C, Schikowski T, Bircher AJ, Burdet L, Gerbase MW, Imboden M, Rochat T, Schmid-Grendelmeier P, Turk AJ, Zemp E, Künzli N, Probst-Hensch N: Rhinitis in Swiss adults is associated with asthma and early life factors, but not second hand tobacco smoke or obesity. Allergol Int 65(2): 192-198, 2016. doi: 10.1016/j.alit.2015.11.004

Hammer-Fomuki E, Mba Okwen P, Ranft U, Gardemann J, Schikowski T: Attitudes of health care professionals towards Mutual Health Organizations: evidence from two regions in the Northwest Province of Cameroon. J Public Health 24(3): 175-183, 2016. doi: 10.1007/2Fs10389-016-0716-9

Ohlwein S, Klümper C, Vossoughi M, Sugiri D, Stolz S, Vierkötter A, Schikowski T, Kara K, Germing A, Quass U, Krämer U, Hoffmann B: Air pollution and diastolic function in elderly women - Results from the SALIA study cohort. Int J Hyg Environ Health 219(4-5): 356-363, 2016. doi: 10.1016/j.ijheh.2016.02.006

Tzivian L, Dlugaj M, Winkler A, Weinmayr G, Hennig F, Fuks KB, Vossoughi M, Schikowski T, Weimar C, Erbel R, Jöckel KH, Moebus S, Hoffmann B, on behalf of the Heinz Nixdorf Recall Study Investigative Group: Long-term air pollution and traffic noise exposures and mild cognitive impairment in older adults: A cross-sectional analysis of the Heinz Nixdorf Recall study. Environ Health Perspect 124(9): 1361-1368, 2016. doi: 10.1289/ehp.1509824

Fuertes E, Markevych I, Bowatte G, Gruzieva O, Gehring U, Becker A, Berdel D, von Berg A, Bergström A, Brauer M, Brunekreef B, Brüske I, Carlsten C, Chan-Yeung M, Dharmage SC, Hoffmann B, Klümper C, Koppelman GH, Kozyrskyj A, Korek M, Kull I, Lodge C, Lowe A, MacIntyre E, Pershagen G, Standl M, Sugiri D, Wijga A, Heinrich J: Residential greenness is differentially associated with childhood allergic rhinitis and aeroallergen sensitization in seven birth cohorts. Allergy 71(10): 1461-1471, 2016. doi: 10.1111/all.12915

Geisel MH, Coassin S, Heßler N, Bauer M, Eisele L, Erbel R, Haun M, Hennig F, Moskau-Hartmann S, Hoffmann B, Jöckel KH, Kedenko L, Kiechl S, Kollerits B, Mahabadi AA, Moebus S, Nürnberg G, Nürnberg P, Paulweber B, Vens M, Willeit J, Willeit K, Klockgether T, Ziegler A, Scherag A, Kronenberg F: Update of the effect estimates for common variants associated with carotid intima media thickness within four independent samples: The Bonn IMT Family Study, the Heinz Nixdorf Recall Study, the SAPHIR Study and the Bruneck Study. Atherosclerosis 249: 83-87, 2016. doi: 10.1016/j.atherosclerosis.2016.03.042

Markevych I, Smith MP, Jochner S, Standl M, Brüske I, von Berg A, Bauer CP, Fuks K, Koletzko S, Berdel D, Heinrich J, Schulz H: Neighbourhood and physical activity in German adolescents: GINIplus and LISAplus. Environ Res 147: 284-293, 2016. doi: 10.1016/j.envres.2016.02.023

Rosenbauer J, Tamayo T, Bächle C, Stahl-Pehe A, Landwehr S, Sugiri D, Krämer U, Maier W, Hermann JM, Holl RW, Rathmann W: Re: Ambient air pollution and early manifestation of type 1 diabetes. Epidemiology 27(4): e25-26, 2016. doi: 10.1097/EDE.0000000000000495

Smith MP, von Berg A, Berdel D, Bauer CP, Hoffmann B, Koletzko S, Nowak D, Heinrich J, Schulz H: Physical activity is not associated with spirometric indices in lung-healthy German youth. Eur Respir J 48(2):428-440, 2016. doi: 10.1183/13993003.01408-2015

Tamayo T, Rathmann W, Stahl-Pehe A, Landwehr S, Sugiri D, Krämer U, Hermann J, Holl RW, Rosenbauer J: No adverse effect of outdoor air pollution on HbA in children and young adults with type 1 diabetes. Int J Hyg Environ Health 219(4-5): 349-355, 2016. doi: 10.1016/j.ijheh.2016.02.002

Thiering E, Markevych I, Brüske I, Fuertes E, Kratzsch J, Sugiri D, Hoffmann B, von Berg A, Bauer CP, Koletzko S, Berdel D, Heinrich J: Associations of residential long-term air pollution exposures and satellite-derived greenness with insulin resistance in German adolescents. Environ Health Perspect 124(8): 1291-1298, 2016. doi: 10.1289/ehp.1509967

Heusinkveld HJ, van Vliet AC, Nijssend PCG, Westerink RHS: In vitro neurotoxic hazard characterisation of dinitrophenolic herbicidesToxicol Lett 252: 62-69, 2016. doi: 10.1016/j.toxlet.2016.04.014

Lang A, Grether-Beck S, Singh M, Kuck F, Jakob S, Kefalas A, Altinoluk-Hambüchen S, Graffmann N, Schneider M, Lindecke A, Brenden H, Felsner I, Ezzahoini H, Marini A, Weinhold S, Vierkötter A, Tigges J, Schmidt S, Stühler K, Köhrer K, Uhrberg M, Haendeler J, Krutmann J, Piekorz RP: MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4. Aging 8(3): 484-509, 2016. doi: 10.18632/aging.100905

Hüls A, Krämer U, Schuster A, Gappa M, Wisbauer M, Müller-Brandes C, Schikowski T, Hoffmann B, von Berg A, Berdel D: Inclusion of children with airway disease for the development of spirometry reference data. Eur Respir J 47(4): 1290-1292, 2016. doi: 10.1183/13993003.01465-2015

Nöske K, Stark H-J, Nevaril L, Berning M, Langbein L, Goyal A, Diederichs S, Boukamp P: Mitotic diversity in homeostatic human interfollicular epidermis. Int J Mol Sci 17(2): 167, 2016. doi: 10.3390/ijms17020167

Vogel CFA, Chang WLW, Kado S, McKulloh K, Vogel H, Wu D, Haarmann-Stemmann T, Yang GX, Leung PSC, Matsumura F, Gershwin ME: Transgenic overexpression of aryl hydrocarbon receptor repressor (AhRR) and AhR-mediated induction of CYP1A1, cytokines and acute toxicity. Environ Health Perspect 124(7): 1071-1083, 2016. doi: 10.1289/ehp.1510194

Orban E, McDonald K, Sutcliffe R, Hoffmann B, Fuks KB, Dragano N, Viehmann A, Erbel R, Jöckel KH, Pundt N, Moebus S: Residential road traffic noise and high depressive symptoms after five years of follow-up: Results from the Heinz Nixdorf Recall study. Environ Health Perspect 124(5): 578-585, 2016. doi: 10.1289/ehp.1409400

Hüls A*, Vierkötter A*, Gao W*, Krämer U, Yang Y, Ding A, Stolz S, Matsui M, Kan H, Wang S, Jin L*, Krutmann J*, Schikowski T*: Traffic-related air pollution contributes to development of facial lentigines: Further epidemiological evidence from Caucasians and Asians. J Invest Dermatol 136(5): 1053-1056, 2016. doi: 10.1016/j.jid.2015.12.045 (* equal contribution) Commentary by Anne Lynn S. Chang

Didovic S*, Opitz FV*, Holzmann B, Förster I, Weighardt H: Requirement of MyD88 signaling in keratinocytes for Langerhans cell migration and initiation of atopic dermatitis-like symptoms in mice. Eur J Immunol 46(4): 981-992, 2016. doi: 10.1002/eji.201545710 (* equal contribution)

Baumann J, Gassmann K, Masjosthusmann S, DeBoer D, Bendt F, Giersiefer S, Fritsche E: Comparative human and rat neurospheres reveal species differences in chemical effects on neurodevelopmental key events. Arch Toxicol 90(6): 1415-1427, 2016. doi: 10.1007/s00204-015-1568-8

Knafo S, Sánchez-Puelles C, Palomer E, Delgado I, Draffin JE, Mingo J, Wahle T, Kaleka K, Mou L, Pereda-Perez I, Klosi E, Faber EB, Chapman HM, Lozano-Montes L, Ortega-Molina A, Ordóñez-Gutiérrez L, Wandosell F, Viña J, Dotti CG, Hall RA, Pulido R, Gerges NZ, Chan AM, Spaller MR, Serrano M, Venero C, Esteban JA: PTEN recruitment controls synaptic and cognitive function in Alzheimer’s models. Nat Neurosci 19(3): 443-453, 2016. doi: 10.1038/nn.4225

Scharf A, Gührs KH, von Mikecz A: Anti-amyloid compounds protect from silica nanoparticle-induced neurotoxicity in the nematode C. elegans. Nanotoxicology 10(4): 426-435, 2016. doi: 10.3109/17435390.2015.1073399

Raaschou-Nielsen O, Beelen R, Wang M, Hoek G, Andersen ZJ, Hoffmann B, Stafoggia M, Samoli E, Weinmayr G, Dimakopoulou K, Nieuwenhuijsen M, Xun WW, Fischer P, Eriksen KT, Sørensen M, Tjønneland A, Ricceri F, de Hoogh K, Key T, Eeftens M, Peeters PH, Bueno-de-Mesquita HB, Meliefste K, Oftedal B, Schwarze PE, Nafstad P, Galassi C, Migliore E, Ranzi A, Cesaroni G, Badaloni C, Forastiere F, Penell J, De Faire U, Korek M, Pedersen N, Östenson CG, Pershagen G, Fratiglioni L, Concin H, Nagel G, Jaensch A, Ineichen A, Naccarati A, Katsoulis M, Trichpoulou A, Keuken M, Jedynska A, Kooter IM, Kukkonen J, Brunekreef B, Sokhi RS, Katsouyanni K, Vineis P: Particulate matter air pollution components and risk for lung cancer. Environ Int 87: 66-73, 2016. doi: 10.1016/j.envint.2015.11.007

De Spirt S, Eckers A, Wehrend C, Micoogullari M, Sies H, Stahl W, Steinbrenner H: Interplay between the chalcone cardamonin and selenium in the biosynthesis of Nrf2- regulated antioxidant enzymes in intestinal Caco-2 cells. Free Radic Biol Med  91: 164-171, 2016. doi: 10.1016/j.freeradbiomed.2015.12.011

von Berg A, Filipiak-Pittroff B, Schulz H, Hoffmann U, Link E, Sußmann M, Schnappinger M, Brüske I, Standl M, Krämer U, Hoffmann B, Heinrich J, Bauer CP, Koletzko S, Berdel D, for the GINIplus Study Group: Allergic manifestation 15 years after early intervention with hydrolyzed formulas – the GINI Study. Allergy 71(2): 210-219, 2016. doi: 10.1111/all.12790

Flexeder C, Thiering E, von Berg A, Berdel D, Hoffmann B, Koletzko S, Bauer CP, Koletzko B, Heinrich J, Schulz H: Peak weight velocity in infancy is negatively associated with lung function in adolescence. Pediatr Pulmonol Pediatr Pulmonol 51(2): 147-156, 2016. doi: 10.1002/ppul.23216

Dittmann KH, Rothmund MC, Paasch A, Mayer C, Fehrenbacher B, Schaller M, Frauenstein K, Fritsche E, Haarmann-Stemmann T, Braeuning A, Rodemann HP: The nuclear aryl hydrocarbon receptor is involved in regulation of DNA-repair and cell survival following treatment with ionizing radiation. Toxicol Lett 240(1): 122-129, 2016. doi: 10.1016/j.toxlet.2015.10.017

Pilz C, Feyerabend T, Sonner J, Redaelli C, Peter K, Kunze A, Haas K, Esser C, Schäkel K, Wick W, Rodewald HR, Lanz TV, Platten M: Normal mast cell numbers in the tissues of AhR-deficient mice. Exp Dermatol 25(1): 62-63, 2016. doi: 10.1111/exd.12864

Hornstein T, Lehmann S, Philipp D, Detmer S, Hoffmann M, Peter C, Wesselborg S, Unfried K, Windolf J, Flohé S, Paunel-Görgülü A: Staurosporine resistance in inflammatory neutrophils is associated with the inhibition of caspase- and proteasome-mediated Mcl-1 degradation. J Leukoc Biol 99(1):163-174, 2016. doi: 10.1189/jlb.3A1114-537RR

Pedersen M, Gehring U, Beelen R, Wang M, Giorgis-Allemand L, Andersen AM, Basagana X, Bernard C, Cirach M, Forastiere F, de Hoogh K, Grazuleviciene R, Gruzieva O, Hoek G, Jedynska A, Klümper C, Kooter IM, Krämer U, Kukkonen J, Porta D, Postma DS, Raaschou-Nielsen O, van Rossem L, Sunyer J, Sørensen M, Tsai MY, Vrijkotte TG, Wilhelm M, Nieuwenhuijsen MJ, Pershagen G, Brunekreef B, Kogevinas M, Slama R: Elemental constituents of particulate matter and newborn's size in eight European cohorts. Environ Health Perspect 124(1): 141-150, 2016. doi: 10.1289/ehp.1409546

Grether-Beck S, Marini A., Jaenicke T, Krutmann J: French maritime pine bark extract (Pycnogenol®) effects on human skin: Clinical and molecular evidence. Skin Pharmacol Physiol 29: 13-17, 2016. doi: 10.1159/000441039

Eckers A, Jakob S, Heiss C, Haarmann-Stemmann T, Goy C, Brinkmann V, Cortese-Krott MM, Sansone R, Esser C, Ale-Agha N, Altschmied J, Ventura N, Haendeler J: The aryl hydrocarbon receptor promotes aging phenotypes. Sci Rep 6: 19618, 2016. doi: 10.1038/srep19618

Übersichtsarbeiten, Buchbeiträge u.a.

Gödecke A, Haendeler J: Intra- and interorgan communication in the cardiovascular system: a special view on redox regulation. Antioxid Redox Signal 2017. doi: 10.1089/ars.2017.6988

Boukamp P, Stark H-J: Nischenprodukt Stammzelle? In: Baden-Württemberg Stiftung (Ed.): 100! Was die Wissenschaft vom Altern weiß. Hirzel-Verlag, Stuttgart, 2016. ISBN: 978-3-7776-2574-4, pp 60-66.

Benfenati E, Berggren E, Fritsche E, Hartung T, Slikker W, Spielmann S, Testai E, Tice RR, Tiramani M, Villenave R: Novel chemical hazard characterisation approaches. EFSA Journal 14(S1): s0506, 2016. doi: 10.2903/j.efsa.2016.s0506

Boix N, Teixido E, Vila-Cejudo M, Ortiz P, Ibanez E, Gomez-Catalan J, Llobet JM, Barenys M: Risk assessment for human embryonic development of triclabendazole residues in milk and cheese in the diet of a rural population in Cajamarca (Peru): A preliminary approach. In: Muñoz-Torrero D, Domínguez À,  Manresa À (Eds.): Recent Advances in Pharmaceutical Sciences VI. Research Signpost, Indien, 2016. ISBN ebook 978-81-308-0566-5, pp 37-47.

Schiavi A and Ventura N: Mitochondrial longevity pathways. In: Olsen A, Gill MS (Eds.): Ageing: Lessons from C. elegans. Springer International Publishing, Switzerland, 2016. ISBN print: 978-3-319-44701-8, pp 83-108.

Stone V, Miller MR, Clift MJD, Elder A, Mills NL, Møller P, Schins RPF, Vogel U, Kreyling WG, Jensen KA, Kuhlbusch TAJ, Schwarze PE, Hoet P, Pietroiusti A, De Vizcaya-Ruiz A, Baeza-Squiban A, Tran CL, Cassee FR: Nanomaterials vs ambient ultrafine particles: an opportunity to exchange toxicology knowledge. Environ Health Perspect 2016. doi: 10.1289/EHP424

Krutmann J, Bouloc A, Sore G, Bernard BA, Passeron T: The skin aging exposome. J Dermatol Sci 2016. doi: 10.1016/j.jdermsci.2016.09.015

Bal-Price A, Lein PJ, Keil KP, Sethi S, Shafer T, Barenys M, Fritsche E, Sachana M, Meek ME: Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity. Neurotoxicology 2016. doi: 10.1016/j.neuro.2016.05.010

Humbert P, Dréno B, Krutmann J, Luger TA, Triller R, Meaume S, Seité S: Recommendations for managing cutaneous disorders associated with advancing age. Clin Interv Aging 12(11): 141-148, 2016. doi: 10.2147/CIA.S96232

Maglioni M, Arsalan N, Ventura N: C. elegans screening strategies to identify pro-longevity interventions. Mech Ageing Dev 157: 60-69, 2016. doi: 10.1016/j.mad.2016.07.010

Heusinkveld HJ, Wahle T, Campbell A, Westerink RHS, Tran L, Johnston H, Stone V, Cassee FR, Schins RPF:  Neurodegenerative and neurological disorders by small inhaled particles. Neurotoxicology 56: 94-106, 2016. doi: 10.1016/j.neuro.2016.07.007

Maglioni S, Ventura N: C. elegans as a model organism for human mitochondrial associated disorders. Mitochondrion 30: 117-125, 2016. doi: 10.1016/j.mito.2016.02.003

Klionski DJ et al.: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12(1): 1-222, 2016. doi: 10.1080/15548627.2015.1100356

Zurek M*, Altschmied J*, Kohlgrüber S, Ale-Agha N, Haendeler J: Role of Telomerase in the cardiovascular system. Genes 7(6): 29, 2016. doi: 10.3390/genes7060029 (* equal contribution)

Zwighaft Z, Reinke H, Asher G: The Liver in the Eyes of a Chronobiologist. J Biol Rhythms 31(2): 115-124, 2016. doi: 10.1177/0748730416633552

Nehr S, Gladtke D, Hellack B, Hermann H, Hoffmann B, Kuhlbusch TAJ, Schins RPF, Wiesen P, Zellner R: Tropospheric aerosols – Current research and future air quality policy. Gefahrst Reinh Luft 76(6): 231-237, 2016. (abstract)

Shaik A, Schiavi A, Ventura N: Mitochondrial autophagy promotes healthy aging (Editorial). Cell Cycle 15(4): 1805-1806, 2016. doi: 10.1080/15384101.2016.1181876

Visser WE, Heuer H, Visser TJ: Triiodothyroacetic Acid Treatment in MCT8 Deficiency: A Word of Nuance (Editorial). Thyroid 26(5): 615-617, 2016. doi: 10.1089/thy.2016.0191

Kermanizadeh A, Gosens G, Johnston H, Danielsen PH, Jacobsen NR, Lenz AG, Fernandes T, Schins RPF, Cassee FR, Wallin H, Kreyling W, Stoeger T, Loft S, Møller P, Tran L, Stone V: A multi-laboratory toxicological assessment of a panel of ten engineered nanomaterials to human health - ENPRA project - the highlights, the limitations and the current and future challenges. J Toxicol Environ Health B Crit Rev 19(1): 1-28, 2016. doi: 10.1080/10937404.2015.112621

Reinke H, Asher G: Circadian Clock Control of Liver Metabolic Functions. Gastroenterology 150(3): 574–580, 2016. doi: 10.1053/j.gastro.2015.11.043

Krutmann J, Schikowski T, Hüls A, Vierkötter A, Grether-Beck S: Umweltinduzierte (extrinsische) Hautalterung. Der Hautarzt 67(2): 99-102, 2016. doi: 10.1007/s00105-015-3750-6

Barenys M, Masjosthusmann S, Fritsche E: Is Intake of Flavonoid-based Food Supplements during Pregnancy Safe for the Developing Child? A Literature Review. Curr Drug Targets 2015, doi: 10.2174/1389450116666150804110049

Esser C: The Aryl Hydrocarbon Receptor in Immunity: Tools and Potential. In: Cuturi MC, Anegon I (Hrsg.): Suppression and Regulation of Immune Responses, Methods and Protocols, Volume II. Humana press New York, 2016. ISBN 978-1-4939-3138-5

Boukamp P, Stark H-J: Nischenprodukt Stammzelle? In: Baden-Württemberg Stiftung (Ed.): 100! Was die Wissenschaft vom Altern weiß. Hirzel-Verlag, Stuttgart, 2016. ISBN: 978-3-7776-2574-4, pp 60-66.
Boix N, Teixido E, Vila-Cejudo M, Ortiz P, Ibanez E, Gomez-Catalan J, Llobet JM, Barenys M: Risk assessment for human embryonic development of triclabendazole residues in milk and cheese in the diet of a rural population in Cajamarca (Peru): A preliminary approach. In: Muñoz-Torrero D, Domínguez À,  Manresa À (Eds.): Recent Advances in Pharmaceutical Sciences VI. Research Signpost, Indien, 2016. ISBN ebook 978-81-308-0566-5, pp 37-47.
Schiavi A and Ventura N: Mitochondrial longevity pathways. In: Olsen A, Gill MS (Eds.): Ageing: Lessons from C. elegans. Springer International Publishing, Switzerland, 2016. ISBN print: 978-3-319-44701-8, pp 83-108.