Aktuelle Publikationen

Originalarbeiten

Spannbrucker T*, Ale-Agha N*, Goy C, Dyballa-Rukes N, Jakobs P, Jander K, Altschmied J, Unfried K, Haendeler J: Induction of a senescent like phenotype and loss of gap junctional intercellular communication by carbon nanoparticle exposure of lung epithelial cells. Exp Gerontol 2018. doi: 10.1016/j.exger.2018.11.017 (*equal contribution)

Hüls A*, Abramson MJ*, Sugiri D, Fuks K, Krämer U, Krutmann J, Schikowski T: Non-atopic eczema in elderly women - Impact of air pollution and genes. J Allergy Clin Immunol 2018. doi: 10.1016/j.jaci.2018.09.031 (* equal contribution)

Torgovnick A*, Schiavi A*, Shaik A#, Kassahun H#, Maglioni S, Rea SL, Johnson TE, Reinhardt HC, Honnen S, Schumacher B, Nilsen H, Ventura N: BRCA1 and BARD1 mediate apoptotic resistance but not longevity upon mitochondrial stress in Caenorhabditis elegans. EMBO Rep 2018. doi: 10.15252/embr.201845856 (*,# equal contribution)

Kühne BA, Puig T, Ruiz-Martínez S, Crous-Masó J, Planas M, Feliu L, Cano A, Garcia ML, Fritsche E, Llobet JM, Gómez-Catalán J, Barenys M: Comparison of migration disturbance potency of epigallocatechin gallate (EGCG) synthetic analogs and EGCG PEGylated PLGA nanoparticles in rat neurospheres. Food Chem Toxicol 2018. doi: 10.1016/j.fct.2018.10.055

Hüls A, Sugiri D, Fuks K, Krutmann J*, Schikowski T*: Lentigines formation in Caucasian women - Interaction between particulate matter and solar ultraviolet radiation J Invest Dermatol 2018. doi: 10.1016/j.jid.2018.09.034 (* equal contribution)

Dekkers S, Ma-Hock L, Lynch I, Russ M, Miller MR, Schins RPF, Keller J, Römer I,  Küttler K, Strauss V, De Jong WH, Landsiedel R, Cassee FR: Differences in the toxicity of cerium dioxide nanomaterials after inhalation can be explained by lung deposition, animal species and nanoforms. Inhal Toxicol 2018. doi: 10.1080/08958378.2018.1516834

Ali AAH, Schwarz-Herzke B, Mir S, Sahlender B, Victor M, Görg B, Schmuck M, Dach K, Fritsche E, Kremer A, von Gall C: Deficiency of the clock gene Bmal1 affects neural progenitor cell migration. Brain Struct Funct 2018. doi: 10.1007/s00429-018-1775-1

Harris CP, von Berg A, Berdel D, Bauer CP, Schikowski T, Koletzko S, Heinrich J, Schulz H, Standl M: Association of dietary fatty acids with blood lipids is modified by physical activity in adolescents: Results from the GINIplus and LISA birth cohort studies. Nutrients 10(10): 1372, 2018. doi: 10.3390/nu10101372

Wu S, Zhang M, Yang X, Peng F, Tan J, Yang Y, Wang L, Hu Y, Peng X, Li J. Liu Y, Lu D, Lou H, Feng Q, Lu Y, Guan Y, Zhang Z, Jiao X, Hamer M, Nijsten T, Zeng C, Adhikar K, Gallo C, Poletti I, Schuler-Faccini L, Bortolin M, Quinteros S, Rothhammer F, Bedoya G, José R, Li H, Krutmann J, Liu F, Kayser M, Ruiz-Linares A, Tang K, Xu S, Zhang L, Jin L, Wang J: Genome-wide association studies and CRISPR/Cas9-mediated gene editing identify regulatory variants influencing eyebrow thickness in humans. Plos Genet 14(9): e1007640, 2018. doi: 10.1371/journal.pgen.1007640

Singh M, Bergmann L, Lang A, Pexa K, Kuck F, Stibane D, Janke L, Ezzahoini H, Lindecke A, Wiek C, Hanenberg H, Köhrer K, von Gall C, Reinke H, Piekorz RP: Gαi3 signaling is associated with sexual dimorphic expression of the clock-controlled output gene Dbp in murine liver. Oncotarget 9(54): 30213-30224, 2018. doi: 10.18632/oncotarget.25727

Narda M, Peno-Mazzarino L, Krutmann J, Trullas C, Granger C: Novel facial cream containing carnosine inhibits formation of advanced glycation end-products in human skin. Skin Pharmacol Physiol 31(6): 324-331, 2018. doi: 10.1159/000492276

Fueldner C, Kohlschmidt J, Riemschneider S, Schulze F, Zoldan K, Esser C, Hauschildt S, Lehmann J: Benzo(a)pyrene attenuates the pattern-recognition-receptor induced proinflammatory phenotype of murine macrophages by inducing IL-10 expression in an aryl hydrocarbon receptor-dependent manner. Toxicology 409: 80-90. doi: 10.1016/j.tox.2018.07.011

Riemschneider S, Kohlschmidt J, Fueldner C, Esser C, Hauschildt S, Lehmann J: Aryl hydrocarbon receptor activation by benzo(a)pyrene inhibits proliferation of myeloid precursor cells and alters the differentiation state as well as the functional phenotype of murine bone marrow-derived macrophages. Toxicol Lett 296: 106-113, 2018. doi: 10.1016/j.toxlet.2018.07.050

Majora M, Sondenheimer K, Knechten M, Uthe I, Esser C, Schiavi A, Ventura N, Krutmann J: HDAC inhibition improves autophagic and lysosomal function to prevent loss of subcutaneous fat in a mouse model of Cockayne syndromeSci Transl Med 10(456): eaam7510, 2018. doi: 10.1126/scitranslmed.aam7510
Full text link: http://stm.sciencemag.org/cgi/content/full/10/456/eaam7510?ijkey=sac1p.cDd82iU&keytype=ref&siteid=scitransmed

Pollet M*, Shaik S*, Mescher M*, Frauenstein K, Tigges J, Braun S, Sondenheimer K, Kaveh M, Bruhs A, Meller S, Homey B, Schwarz A, Esser C, Douki T, Vogel CF, Krutmann J, Haarmann-Stemmann T: The AHR represses nucleotide excision repair and apoptosis and contributes to UV-induced skin carcinogenesis. Cell Death Differ 25: 1823-1836, 2018. doi: 10.1038/s41418-018-0160-1 (* equal contribution)


Forns J, Sunyer J, Garcia-Esteban R, Porta D, Ghassabian A,  Giorgis-Allemand L, Gong T, Gehring U, Sørensen M, Standl M, Sugiri D, Almqvist C, Andiarena A, Badaloní C, Beelen R, Berdel D, Cesaroni G, Charles M-A, Eriksen KT, Estarlich M, Fernandez MF, Forhan A, Jaddoe VWV, Korek M,  Lichtenstein P, Lertxundi A, Lopez-Espinosa MJ, Markevych I, de Nazelle A, Raaschou-Nielsen O, Nieuwenhuijsen M, Pérez-Lobato R, Philippat C, Slama R, Tiesler CM,  Verhulst FC, von Berg A, Vrijkotte T, Nybo Andersen AM, Heude B, Krämer U, Heinrich J, Tiemeier H, Forastiere F, Pershagen G, Brunekreef B,  Guxens M: Air pollution exposure during pregnancy and symptoms of attention deficit and hyperactivity disorder in children in Europe. Epidemiology 29(5): 618-626, 2018. doi: 10.1097/EDE.0000000000000874

Nguyen TD, Schwarzer M, Schrepper A, Amorim PA, Blum D, Hain C, Faerber G, Haendeler J, Altschmied J, Doenst T: Increased Protein Tyrosine Phosphatase 1B (PTP1B) activity and cardiac insulin resistance precede mitochondrial and contractile dysfunction in pressure-overloaded hearts. J Am Heart Assoc 7 (13): e008865, 2018. doi: 10.1161/JAHA.118.008865

Hellwig C, Barenys M, Baumann J, Gassmann K, Casanellas L, Kauer G, Fritsche E: Culture of human neurospheres in 3D scaffolds for developmental neurotoxicity testing. Toxicol In Vitro 52: 106-115, 2018. doi: 10.1016/j.tiv.2018.06.002

Ale-Agha N#, Goy C#, Jakobs P#, Spyridopoulos I, Gonnissen S, Dyballa-Rukes N, Aufenvenne K, von Ameln F, Zurek M, Spannbrucker T, Eckermann O, Jakob S, Gorressen S, Abrams M, Grandoch M, Fischer JW, Köhrer K, Deenen R, Unfried K, Altschmied J*, Haendeler J*: CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system - New mode of action for caffeine. Plos Biol 16(6): e2004408. doi: 10.1371/journal.pbio.2004408 (#, * equal contribution)

Schnass W, Hüls A, Vierkötter A, Krämer U, Krutmann J, Schikowski T: Traffic-related air pollution and eczema in the elderly: Findings from the SALIA cohort. Int J Hyg Environ Health 221(6): 861-867, 2018. doi: 10.1016/j.ijheh.2018.06.002

Hanžić N, Horvat A, Bibić J, Unfried K, Jurkin T, Dražić G, Marijanović I, Slade N, Gotić M: Syntheses of gold nanoparticles and their impact on the cell cycle in breast cancer cells subjected to megavoltage X-ray irradiation. Mater Sci Eng C 91: 486-495, 2018. doi: 10.1016/j.msec.2018.05.066

Bauer C, Abdul Pari AA, Umansky V, Utikal J, Boukamp P, Augustin HG, Goerdt S, Géraud C, Felcht M: T-lymphocyte profiles differ between keratoacanthomas and invasive squamous cell carcinomas of the human skin. Cancer Immunol Immunother 67(7): 1147-1157, 2018. doi: 10.1007/s00262-018-2171-7

Bowatte G, Markevych I, Standl M, Dharmage SC, Koletzko S, Lehmann I, Bauer CP, Schikowski T, von Berg A, Berdel D, Heinrich J: Hygienic behavior and allergic sensitization in German adolescents. Allergy 73(9):1915-1918, 2018. doi: 10.1111/all.13492

Masjosthusmann S, Becker D, Petzuch B, Klose J, Siebert C, Deenen R, Barenys M, Baumann J, Dach K, Tigges J, Hübenthal U, Köhrer K, Fritsche E: A transcriptome comparison of time-matched developing human, mouse and rat neural progenitor cells reveals human uniqueness. Toxicol Appl Pharmacol 354: 40-55, 2018. doi: 10.1016/j.taap.2018.05.009

Bühlmeier J, Harris C, Koletzko S, Lehmann I, Bauer CP, Schikowski T, von Berg A, Berdel D, Heinrich J, Hebebrand J, Föcker M, Standl M, Libuda L: Dietary acid load and mental health outcomes in children and adolescents: Results from the GINIplus and LISA birth cohort studies. Nutrients 2018 10(5): E582. doi: 10.3390/nu10050582

Mayerl S, Schmidt M, Doycheva D, Darras VM, Hüttner SS, Boelen A, Visser TJ, Kaether C, Heuer H, von Maltzahn J: Thyroid hormone transporters MCT8 and OATP1C1 control skeletal muscle regeneration. Stem Cell Rep 10(6): 1959-1974, 2018. doi: 10.1016/j.stemcr.2018.03.021

Kotz S, Kullmann M, Kalayda GV, Dyballa-Rukes N, Jaehde U, Metzger S: Optimized two-dimensional gel electrophoresis in an alkaline pH range improves the identification of intracellular CFDA-cisplatin-protein adducts in ovarian cancer cells. Electrophoresis 39(12): 1488-1496, 2018. doi: 10.1002/elps.201700377

Thacher JD, Gehring U, Gruzieva O, Standl M, Pershagen G, Bauer CP, Berdel D, Keller T, Koletzko S, Koppelman GH, Kull I, Lau S, Lehmann I, Maier D, Schikowski T, Wahn U, Wijga AH, Heinrich J, Bousquet J, Anto JM, von Berg A, Melén E, Smit HA, Keil T, Bergström A: Maternal smoking during pregnancy and early childhood and development of asthma and rhinoconjunctivitis - a MeDALL project. Environ Health Perspect 126(4): 047005, 2018. doi: 10.1289/EHP2738

Smith MP, Standl M, Berdel D, von Berg A, Bauer CP, Schikowski T, Koletzko S, Lehmann I, Krämer U, Heinrich J, Schulz H: Handgrip strength is associated with improved spirometry in adolescents. Plos One 13(4): e0194560, 2018. doi: 10.1371/journal.pone.0194560

Hüls A, Klümper C, MacIntyre EA, Brauer M, Melén E, Bauer M, Berdel D, Bergström A, Brunekreef B, Chan-Yeung M, Fuertes E, Gehring U, Gref A, Heinrich J, Standl M, Lehmann I, Kerkhof M, Koppelman GH, Kozyrskyj AL, Pershagen G, Carlsten C, Krämer U, Schikowski T; TAG Study Group: Atopic dermatitis: Interaction between genetic variants of GSTP1, TNF, TLR2, and TLR4 and air pollution in early life. Pediatr Allergy Immunol 29(6): 596-605, 2018. doi: 10.1111/pai.12903

Perkins TN, Peeters PM, Albrecht C, Schins RPF, Dentener MA, Mossman BT, Wouters EFM, Reynaert NL: Crystalline silica alters Sulfatase-1 expression in rat lungs which influences hyper-proliferative and fibrogenic effects in human lung epithelial cells. Toxicol Appl Pharmacol 348: 43-53, 2018. doi: 10.1016/j.taap.2018.04.011

Stöckmann D, Spannbrucker T, Ale-Agha N, Jakobs P, Goy C, Dyballa-Rukes N, Hornstein T, Kümper A, Kraegeloh A, Haendeler J, Unfried K: Non-canonical activation of the epidermal growth factor receptor by carbon nanoparticles. Nanomaterials 8(4): 267, 2018. doi: 10.3390/nano8040267

Lanzinger S, Rosenbauer J, Sugiri D, Schikowski T, Treiber B, Klee D, Rathmann W, Holl RW: Impact of long-term air pollution exposure on metabolic control in children and adolescents with type 1 diabetes: results from the DPV registry. Diabetologia 61(6): 1354-1361, 2018. doi: 10.1007/s00125-018-4580-8

Lademann J, Knorr F, Patzelt A, Meinke MC, Richter H, Krutmann J, Rühl E, Doucet O: Laser scanning microscopic investigations of the decontamination of soot nanoparticles from the skin. Skin Pharmacol Physiol 31(2): 87-94, 2018. doi: 10.1159/000485900

Ermakova YG, Pak VV, Bogdanova YA, Kotlobay AA, Yampolsky IV, Shokhina AG, Panova AS, Marygin RA, Staroverov DB, Bilan DS, Sies H, Belousov VV: SypHer3s: a genetically encoded fluorescent ratiometric probe with enhanced brightness and an improved dynamic range. Chem Commun (Camb) 54(23): 2898-2901, 2018. doi: 10.1039/c7cc08740c

Bal-Price A, Hogberg HT, Crofton KM, Daneshian M, FitzGerald RE, Fritsche E, Heinonen T, Hougaard Bennekou S, Klima S, Piersma AH, Sachana M, Shafer TJ, Terron A, Monnet-Tschudi F, Viviani B, Waldmann T, Westerink RHS, Wilks MF, Witters H, Zurich MG, Leist M: Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity. ALTEX 2018. doi: 10.14573/altex.1712081

Fritsche E, Grandjean P, Crofton KM, Aschner M, Goldberg A, Heinonen T, Hessel EVS, Hogberg H, Bennekou SH, Lein PJ, Leist M, Mundy WR, Paparella M, Piersma AH, Sachana M, Schmuck G, Solecki R, Terron A, Monnet-Tschudi F, Wilks MF, Witters H, Zurich MG, Bal-Price A: Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes. Toxicol Appl Pharmacol 2018. doi: 10.1016/j.taap.2018.02.004

Baker N, Boobis A, Burgoon L, Carney E, Currie R, Fritsche E, Knudsen T, Laffont M, Piersma AH, Poole A, Schneider S, Daston G: Building a developmental toxicity ontology. Birth Defects Res Part B-Dev Reprod Toxicol 110(6): 502-518, 2018. doi: 10.1002/bdr2.1189

Harder L, Dudazy-Gralla S, Müller-Fielitz H, Hjerling Leffler J, Vennström B, Heuer H, Mittag J: Maternal thyroid hormone is required for parvalbumin neurone development in the anterior hypothalamic area. J Neuroendocrinol 30(3): e12573, 2018. doi: 10.1111/jne.12573

Liu W, Pan X, Vierkötter A, Guo Q, Wang X, Wang Q, Seité S, Moyal D, Schikowski T, Krutmann J: A time-series study of the effect of air pollution on outpatient visits for acne vulgaris in Beijing. Skin Pharmacol Physiol 31: 107-113, 2018. doi: 10.1159/000484482

Hüls A, Vierkötter A, Sugiri D, Abramson MJ, Ranft U, Krämer U, Schikowski T: The role of air pollution and lung function on cognitive impairment. Eur Respir J 51: 1701963, 2018. doi: 10.1183/13993003.01963-2017

Ispanixtlahuatl-Meráz O, Schins RPF, Chirino YI: Cell type specific cytoskeleton disruption induced by engineered nanoparticles. Environ Sci Nano 5: 228-245, 2018. doi: 10.1039/C7EN00704C

Piechulek A, von Mikecz A: Life span-resolved nanotoxicology enables identification of age-associated neuromuscular vulnerabilities in the nematode Caenorhabditis elegans. Environ Pollut 233: 1095-1103, 2018. doi: 10.1016/j.envpol.2017.10.012

Filipiak-Pittroff B, Koletzko S, Krämer U, Standl M, Bauer C-P, Berdel D, von Berg A: Full breastfeeding and allergies from infancy until adolescence in the GINIplus cohort. Pediatr Allergy Immunol 29(1): 96-101, 2018. doi: 10.1111/pai.12798

Kassahun H, SenGupta T, Schiavi A, Maglioni S, Skjeldam HK, Arczewska K, Brockway NL, Estes S, Eide L, Ventura N, Nilsen H: Constitutive MAP-kinase activation suppresses germline apoptosis in NTH-1 DNA glycosylase deficient C. elegans. DNA Repair (Amst) 61: 46-55, 2018. doi: 10.1016/j.dnarep.2017.11.009

Tischer C, Dadvand P, Basagana X, Fuertes E, Bergström A, Gruzieva O, Melen E, Berdel D, Heinrich J, Koletzko S, Markevych I, Standl M, Sugiri D, Cirugeda L, Estarlich M, Fernández-Somoano A, Ferrero A, Ibarlueza J, Lertxundi A, Tardón A, Sunyer J, Anto JM: Urban upbringing and childhood respiratory and allergic conditions: A multi-country holistic study. Environ Res 161: 276-283, 2018. doi: 10.1016/j.envres.2017.11.013

Proquin H, Jetten MJ, Jonkhout MCM, Garduño-Balderas LG, Briedé JJ, de Kok TM, Chirino YI, van Loveren H: Gene expression profiling in colon of mice exposed to food additive titanium dioxide (E171). Food Chem Toxicol 111: 153-165, 2018. doi: 10.1016/j.fct.2017.11.011

Fülle L, Steiner N, Funke M, Gondorf F, Pfeiffer F, Siegl J, Opitz FV, Haßel SK, Erazo AB, Schanz O, Stunden HJ, Blank M, Gröber C, Händler K, Beyer M, Weighardt H, Latz E, Schultze JL, Mayer G, Förster I: RNA aptamers recognizing murine CCL17 inhibit T cell chemotaxis and reduce contact hypersensitivity in vivo. Mol Ther 26(1): 95-104, 2018. doi: 10.1016/j.ymthe.2017.10.005

Hendgen-Cotta UB, Esfeld S, Jastrow H, Totzeck M, Altschmied J, Goy C, Haendeler J, Winterhager E, Rassaf T: Mouse cardiac mitochondria do not separate in subsarcolemmal and interfibrillar subpopulations. Mitochondrion 38: 1-5, 2018. doi: 10.1016/j.mito.2017.07.005

Übersichtsarbeiten, Buchbeiträge u.a.

Esser C, Lawrence BP, Sherr DH, Perdew GH, Puga A, Barouki R, Coumoul X: Old receptor, new tricks-the ever-expanding universe of aryl hydrocarbon receptor functions. Report from the 4th AHR Meeting, 29-31 August 2018 in Paris, France. Int J Mol Sci 19(11): 3603, 2018. doi: 10.3390/ijms19113603

Barenys M, Fritsche E: A historical perspective on the use of stem/progenitor cell-based in vitro methods for neurodevelopmental toxicity testing. Toxicol Sci 165(1): 10-13, 2018. doi: 10.1093/toxsci/kfy170

Fritsche E, Barenys M, Klose J, Masjosthusmann S, Nimtz L, Schmuck M, Wuttke S, Tigges J: Current availability of stem cell-based in vitro methods for developmental neurotoxicity (DNT) testing. Toxicol Sci 165(1): 21-30, 2018. doi: 10.1093/toxsci/kfy178

Fritsche E, Barenys M, Klose J, Masjosthusmann S, Nimtz L, Schmuck M, Wuttke S, Tigges J: Development of the concept for stem cell-based developmental neurotoxicity evaluation. Toxicol Sci 165(1): 14-20, 2018. doi: 10.1093/toxsci/kfy175

Sies H: On the history of oxidative stress: Concept and some aspects of current development. Curr Opinion Toxicol 7: 122-126, 2018. doi: 10.1016/j.cotox.2018.01.002

Bal-Price A, Fritsche E: Editorial: Developmental neurotoxicity. Toxicol Appl Pharmacol 354: 1-22018. doi: 10.1016/j.taap.2018.07.016

Pollet M, Krutmann J, Haarmann-Stemmann T: Commentary: Usage of mitogen-activated protein kinase small inhibitors: More than just inhibition!” Front Pharmacol 9: 935, 2018. doi: 10.3389/fphar.2018.00935

Masjosthusmann S, Barenys M, El-gamal M, Geerts L, Gorreja A, Kühne B, Marchetti N, Tigges J, Witters H, Fritsche E: Literature review and appraisal on alternative neurotoxicity testing methods. EFSA Supporting Publications 2018. doi: 10.2903/sp.efsa.2018.EN-1410

Sondenheimer K, Krutmann J: Novel means for photoprotection. Front Med 5: 162, 2018. doi: 10.3389/fmed.2018.00162

Schneider A, Rückerl R, Standl M, Markevych I, Hoffmann B, Moebus S, Jöckel KH, Weber A, Herr C, Heißenhuber A, Nennstiel-Ratzel U, Heinze S, Schulz C, Kolossa-Gehring M, Niemann H, Gößwald A, Schikowski T, Hüls A, Sugiri D, Peters A: Epidemiological studies with environmental relevance in Germany. Bundesgesundheitsblatt-Gesund 61(6): 697-709, 2018. doi: 10.1007/s00103-018-2740-0

Mescher M, Haarmann-Stemmann T: Modulation of CYP1A1 metabolism: From adverse health effects to chemoprevention and therapeutic options. Pharmacol Ther 187: 71-87, 2018. doi: 10.1016/j.pharmthera.2018.02.012

Diepgen TL, Kresken J, Krutmann J, Merk HF, Senger E, Surber C, Szeimies RM; GD Task Force "Licht.Hautkrebs.Prävention" of the Society for Dermopharmacy: Commentary on the "Evidence- and Consensus-Based (S3) Guidelines for the Treatment of Actinic Keratosis" published by the International League of Dermatological Societies in cooperation with the European Dermatology Forum. Skin Pharmacol Physiol 31(3): 144-146, 2018. doi: 10.1159/000486687

Heinrich J, Schikowski T: COPD patients as vulnerable subpopulation for exposure to ambient air pollution. Curr Environ Health Rep 5(1): 70-76, 2018. doi: 10.1007/s40572-018-0178-z

Esser C, Haarmann-Stemmann T, Hochrath K, Schikowski T, Krutmann J: AHR and the issue of immunotoxicity. Curr Opinion Toxicol 10: 91-97, 2018. doi: 10.1016/j.cotox.2018.03.001

Nakamura M*, Haarmann-Stemmann T*, Krutmann J, Morita A: Alternative test models for skin aging research. Exp Dermatol 27: 495-500, 2018. doi: 10.1111/exd.13519

Bal-Price A, Hogberg HT, Crofton KM, Daneshian M, FitzGerald RE, Fritsche E, Heinonen T, Hougaard Bennekou S, Klima S, Piersma AH, Sachana M, Shafer TJ, Terron A, Monnet-Tschudi F, Viviani B, Waldmann T, Westerink RHS, Wilks MF, Witters H, Zurich MG, Leist M: Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity. ALTEX 35(3): 306-352, 2018. doi: 10.14573/altex.1712081

Fritsche E, Grandjean P, Crofton KM, Aschner M, Goldberg A, Heinonen T, Hessel EVS, Hogberg H, Bennekou SH, Lein PJ, Leist M, Mundy WR, Paparella M, Piersma AH, Sachana M, Schmuck G, Solecki R, Terron A, Monnet-Tschudi F, Wilks MF, Witters H, Zurich MG, Bal-Price A: Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes. Toxicol Appl Pharmacol 354: 3-6, 2018. doi: 10.1016/j.taap.2018.02.004

von Mikecz A: Lifetime eco-nanotoxicology in an adult organism: where and when is the invertebrate C. elegans vulnerable? Environ Sci-Nano 5: 616-622, 2018. doi: 10.1039/C7EN01061C

Krutmann J, Sondenheimer K, Grether-Beck S, Haarmann-Stemmann T: Combined, simultaneous exposure to radiation within and beyond the UV spectrum: A novel approach to better understand skin damage by natural sunlight. In: Merk J, Krutmann J (Eds.): Environment and skin. Springer International Publishing, Switzerland, 2018. ISBN: 9783319431000, pp 11-16.

Pavez Loriè E, Stark H-J, Berning M, Boukamp P: Skin squamous cell carcinoma models: The role in combating the disease. In: Marques A, Pirraco RP, Cerqueria MT, Reis RL (Eds.): Skin tissue models. Elsevier, London, UK. ISBN 9780128105450,  pp 151-173.

Heiss C, Spyridopoulos I, Haendeler J: Interventions to slow cardiovascular aging: Dietary restriction, drugs and novel molecules. Exp Gerontol 109: 108-118, 2018. doi: 10.1016/j.exger.2017.06.015

Reinke H, Asher G: Liver Size: Waning by day, waxing by night. Hepatology 67(1): 441-443, 2018. doi: 10.1002/hep.29506